The Inclusion Body Solubilization Reagent dissolves inclusion body aggregates resulting from the expression of recombinant proteins in bacteria. This reagent has demonstrated exceptional ablility to solubilize inclusion bodies. Once dissolved, proteins can be analyzed by SDS-PAGE, quantified or further purified for refolding.

Inclusion bodies can be released from bacterial cells using Norgen's Cell Lysis Reagent (available separately). Norgen's Inclusion Body Protein Isolation Kits can also be used as complete kits for  cell disruption, inclusion body solubilisation and purification using spin column chromatography