For rapid and simple collection, and preservation of urine samples
For research use only and NOT intended for in vitro diagnostics.
Urine Collection and Stabilization Devices
For rapid and simple collection, and preservation of urine samples
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Features and Benefits
- Macromolecules can be stabilized at room temperature
- Compatible with many nucleic acid and protein purification methods
- Preservative is available in a single dose liquid format (ampoule)
- Preservative is also available in a dried format in tubes - Urine Collection and Stabilization Tubes
- Urine Collection and Stabilization Devices are available in 4 convenient sizes: 5 cc tubes, 15 cc tubes, 50 cc tubes, and 120 cc cups
Norgen's Urine Stabilizer is designed to slow the degradation of macromolecules in urine samples. The Urine Stabilizer may reduce the need to immediately process or freeze samples and thus allows the samples to be shipped to centralized testing facilities at ambient temperatures.
Norgen's Urine Stabilizer is available in 2 convenient formats:
1. Urine Stabilizer Single Dose Ampules
With this product, Norgen's Urine Stabilizer is supplied in a liquid format in single dose ampoules. The user simply collects 5 - 50 mL of urine into a urine collection container and adds the contents of the Urine Stabilizer Single Dose (Cat# 18126). The urine and stabilizer are then mixed.
2. Urine Collection and Preservation Tubes
Norgen's Urine Stabilizer is also available in a dried format in Norgen’s Urine Collection and Stabilization Tubes. The user simply collects urine into the tubes and mixes gently until the orange stabililzer pellet in the tube has dissolved. Norgen's Urine Collection and Stabilization Tubes are available in 3 convenient sizes:
- 5 cc tubes, 1 - 5 mL of urine
- 15 cc tubes, 5 - 15 mL of urine
- 50 cc tubes, 5 - 45 mL of urine
- 120 cc cup, 100 - 120 mL of urine
Details
Supporting Data
Figure 1. Stability of DNA in Norgen's Urine Stabilizer.
Urine samples were collected from numerous healthy donors and pooled, and then the urine was aliquoted into 5 mL aliquots in Norgen's Urine Collection and Stabilization Tubes (5 cc) (Cat# 18116). The stabilized urine was stored at -20°C, 4°C and room temperature for up to 48 months. Urine DNA was subsequently isolated at time 0, 1 month, 2 months, 4 months, 8 months, 12 months, 16 months, 20 months and 24 months from the stabilized urine using Norgen's Urine DNA Isolation Kit (Slurry Format) (Cat# 48800). To test the integrity of the purified DNA, 3 μL of each elution was used in a 20 μL Taqman PCR reaction run on a CFX96 Touch Real-Time PCR Detection System (Bio-Rad) using Norgens 2X PCR Master Mix with 5s rRNA primers. As it can be seen, all the DNA samples were successfully amplified.
Figure 2. Stability of RNA in Norgen's Urine Stabilizer.
Urine samples were collected from numerous healthy donors and pooled, and then the urine was aliquoted into 5 mL aliquots in Norgen's Urine Collection and Stabilization Tubes (5 cc) (Cat. 18116). The stabilized urine was stored at -20°C, 4°C, and room temperature for up to 24 months. Urine RNA was then subsequently isolated at time 0, 1 month, 2 months, 4 months, 8 months, 12 months, 16 months, and 24 months from the preserved urine using Norgen's Urine Total RNA Purification Maxi Kit (Slurry Format) (Cat. 29600).
Select Urine Tested with the Norgen Urine Collection and Stabilization Tubes
Mouse
Lynx
Wolf
Urine collected from snow
Available Sizes and Formats
- Urine Collection and Stabilization Tubes (5 cc) - Urine inputs from 1 - 5 mL
Storage Conditions and Product Stability
All tubes should be kept tightly sealed and stored at room temperature (15 – 25°C) for up to 2 years without any reduction in performance.
| Kit Components | Cat. 18118 (50 tubes) | Cat. 18122 (50 tubes) | Cat. 18113 (50 tubes) | Cat. 18126 (50 tubes) | Cat. 18129 (1 cup) |
|---|---|---|---|---|---|
| Urine Collection and Preservation Tubes (5 cc) | 50 | - | - | - | - |
| Urine Collection and Stabilization Tubes (15 cc) | - | 50 | - | - | - |
| Urine Collection and Stabilization Tubes (50 cc) | - | - | 50 | - | - |
| Urine Stabilizer Single Dose | - | - | - | 50 | - |
| Urine Collection and Stabilization Cup (120 cc) | - | - | - | - | 1 |
| ID Labels | 50 | - | - | 50 | - |
| Product Insert | 1 | 1 | 1 | 1 | 1 |
Documentation
- in a timely manner that considers the person's accessibility needs due to disability; and
- at a cost that is no more than the regular cost charged to other persons
FAQs
| Title | Urinary miRNA Analysis for Clear Cell Renal Cell Carcinoma: miR-20a as a Key Endogenous Normalizer |
| Citation | International Journal of Molecular Sciences 2026. |
| Authors | Giovanni Cochetti, Giacomo Vannuccini, Matteo Mearini, Alessio Paladini, Francesca Cocci, Raffaele La Mura, Daniele Mirra, Giuseppe Giardino and Ettore Mearini |
| Title | Urine-Based cfDNA Ensemble Modeling for Early Detection of Bladder Cancer Using Whole-Genome Methylation Sequencing |
| Citation | Cancers 2026. |
| Authors | Taehoon Kim, Dongju Shin, Hyun Kyu Ahn, Young Joon Moon, Duhee Bang, and Kwang Hyun Kim |
| Title | Urine Metabolomics and Machine Learning Identify Metabolic Features and Potential Biomarkers of HTLV-1-Associated Myelopathy (HAM) |
| Citation | International Journal of Molecular Sciences 2026. |
| Authors | Lorena Abreu Fernandes,Youko Nukui, Rosa Maria Marcusso, Michel Elyas, Jung Haziot, Augusto César Penalva de Oliveira, Jorge Casseb, Patricia Bianca Clissa, Ana Olivia de Souza, Silas G. Villas-Boas and Sabri Saeed Sanabani |
| Title | Effect of Bladder Injections of Botulinum Neurotoxin A on Biomarkers Associated with Inflammation and Urinary Infections in Patients with Neurogenic Detrusor Overactivity-Associated Incontinence: A Pilot, Prospective, Human Study |
| Citation | International Journal of Molecular Sciences 2026. |
| Authors | Sotirios Gatsos, Elena Constantinou, Dimitrios Koutsoumparis, Michael Samarinas, Konstantinos Drosos, Maria Papaioannou, Andigoni Malousi, Eudoxia G. Hatzivassiliou, and Apostolos Apostolidis |
| Title | Does the urinary microbiome reflect the bladder-cancer-associated microbiome? Characterizing the microbiome in urine and cancer tissue in bladder cancer |
| Citation | Urologic Oncology 2026. |
| Authors | Ahmed A. Hussein, Yakov Klugman, Jordan Carlson,Tariq A. Bhat, Zhe Jing, Eduardo Cortes Gomez, Prashant K. Singh, Jianmin Wang, Justine Jacobi, Gary Smith, David Goodrich, Khurshid A. Guru |
| Title | Liquid Biopsy in Clear Cell Renal Cell Carcinoma: Diagnostic Potential of Urinary miRNAs |
| Citation | Cancers 2026. |
| Authors | Giacomo Vannuccini, Alessio Paladini, Matteo Mearini, Francesca Cocci, Giuseppe Giardino, Paolo Mangione, Vincenza Maulà, Daniele Mirra, Ettore Mearini and Giovanni Cochetti |
| Title | Catapult-like DNA actuator for highly stable and ultrasensitive detection of urinary miRNA |
| Citation | Chemical Engineering Journal 2025. |
| Authors | Jae Chul Park a 1, Sungwook Park a 1, Seunghwan Bang a b, Hyunro Kim a c, Yongjin Lee a c, Min Gu Park e, Sung Goo Yoon e, Youngdo Jeong a d, Hojun Kim a b, Seok Ho Kang e, Kwan Hyi Lee |
| Title | Discrepancies in Biomarker Identification in Peak Picking Strategies in Untargeted Metabolomics Analyses of Cells, Tissues, and Biofluids |
| Citation | Journal of Proteome research 2025. |
| Authors | Iqbal Mahmud, Taylor A. Harmon Laurel E. Meke Timothy J. Garrett |
| Title | Persistent urinary metabolic signatures in children with type 1 diabetes |
| Citation | Neuroscience Research 2025. |
| Authors | Ernesto S. Nakayasu, Javier E. Flores, Lisa M. Bramer, Jackson Chin, Young-Mo Kim, Farooq Syed, Erika M. Zink, Brigitte I. Frohnert, Carmella Evans-Molina, Paul B. Kaplowitz, Fran E. Cogen, Rembert Pieper, Thomas O. Metz, Bobbie-Jo M. Webb-Robertson |
| Title | Risk Classification for Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) Using Machine Learning Based Predictions |
| Citation | Urology 2024. |
| Authors | Laura E. Lamb a b, Joseph J. Janicki c, Sarah N. Bartolone d, Elijah P. Ward d, Nitya Abraham e, Melissa Laudano e, Christopher P. Smith f, Kenneth M. Peters a d c, Bernadette M.M. Zwaans a d, Michael B. Chancellor |