Urine Collection and Preservation Devices For rapid and simple collection, and preservation of urine samples For research use only and NOT intended for in vitro diagnostics. Powered by Bioz Urine Collection and Preservation Devices For rapid and simple collection, and preservation of urine samples Price USD$525.00 SKU 18118 Format 5 cc 15 cc 50 cc Single Dose Preservative 120 cc Cup Size 50 Tubes Quantity Request sample Overview Details Documentation Citations Overview RNA/microRNA/DNA/Proteins are preserved for more than 2 years at room temperature in Norgen's Urine Preservative Compatible with most DNA, Total RNA, microRNA and protein isolation methods Preservative is available in a single dose liquid format (ampule) Preservative is also available in a dried format in tubes - Urine Collection and Preservation Tubes Urine Collection and Preservation Devices are available in 4 convenient sizes: 5 cc tubes, 15 cc tubes, 50 cc tubes, and 120 cc cups Norgen's Urine Preservative is designed for the rapid preservation of DNA, RNA, microRNA and proteins from fresh urine samples. In addition, the Urine Preservative eliminates the need to immediately process or freeze samples and allows the samples to be shipped to centralized testing facilities at ambient temperatures. The components of the Urine Preservative allow samples to be stored for over 2 years at room temperature with no detected degradation of urine DNA, RNA or proteins. Norgen's Urine Preservative is available in 2 convenient formats: 1. Urine Preservative Single Dose Ampules With this product Norgen's Urine Preservative is supplied in a liquid format in single dose ampules. The user simply collects 5 - 50 mL of urine into a urine collection container and adds the contents of the Urine Preservative Single Dose (Cat# 18126). The urine and preservative are then mixed, and the urine nucleic acids and proteins are preserved at room temperature. 2. Urine Collection and Preservation Tubes Norgen's Urine Preservative is also available in a dried format in Norgen’s Urine Collection and Preservation Tubes. The user simply collects urine into the tubes and mixes gently until the orange preservative pellet in the tube has dissolved. Norgen's Urine Collection and Preservation Tubes are available in 3 convenient sizes: 5 cc tubes, 1 - 5 mL of urine 15 cc tubes, 5 - 15 mL of urine 50 cc tubes, 5 - 45 mL of urine 120 cc cup, 100 - 120 mL of urine Details Supporting Data Previous Figure 1. Stability of DNA in Norgen's Urine Preservative. Urine samples were collected from numerous healthy donors and pooled, and then the urine was aliquoted into 5 mL aliquots in Norgen's Urine Collection and Preservation Tubes (5 cc) (Cat# 18116). The preserved urine was stored at -20°C, 4°C and room temperature for up to 48 months. Urine DNA was subsequently isolated at time 0, 1 month, 2 months, 4 months, 8 months, 12 months, 16 months, 20 months and 24 months from the preserved urine using Norgen's Urine DNA Isolation Kit (Slurry Format) (Cat# 48800). To test the integrity of the purified DNA, 3 μL of each elution was used in a 20 μL Taqman PCR reaction run on a CFX96 Touch Real-Time PCR Detection System (Bio-Rad) using Norgens 2X PCR Master Mix with 5s rRNA primers. As it can be seen, all the DNA samples were successfully amplified. Furthermore, the quality of the concentrated and preserved urine DNA stored at all 3 temperatures did not significantly change from 0 months to 24 months, as indicated by the fact that the Ct value remained consistent. Figure 2. Stability of RNA in Norgen's Urine Preservative. Urine samples were collected from numerous healthy donors and pooled, and then the urine was aliquoted into 5 mL aliquots in Norgen's Urine Collection and Preservation Tubes (5 cc) (Cat. 18116). The preserved urine was stored at -20°C, 4°C, and room temperature for up to 24 months. Urine RNA was then subsequently isolated at time 0, 1 month, 2 months, 4 months, 8 months, 12 months, 16 months, and 24 months from the preserved urine using Norgen's Urine Total RNA Purification Maxi Kit (Slurry Format) (Cat. 29600). Next Click for expanded view Select Urine Tested with the Norgen Urine Collection and Preservation Tubes Human Mouse Lynx Wolf Urine collected from snow Available Sizes and Formats Urine Collection and Preservation Tubes (5 cc) - Urine inputs from 1 - 5 mL Storage Conditions and Product Stability All tubes should be kept tightly sealed and stored at room temperature (15 – 25°C) for up to 2 years without any reduction in performance. Kit Components Cat. 18118 (50 tubes) Cat. 18122 (50 tubes) Cat. 18113 (50 tubes) Cat. 18126 (50 tubes) Cat. 18129 (1 cup) Urine Collection and Preservation Tubes (5 cc) 50 - - - - Urine Collection and Preservation Tubes (15 cc) - 50 - - - Urine Collection and Preservation Tubes (50 cc) - - 50 - - Urine Preservative Single Dose - - - 50 - Urine Collection and Preservation Cup (120 cc) - - - - 1 ID Labels 50 - - 50 - Product Insert 1 1 1 1 1 Documentation PROTOCOLS (18118) Urine Collection and Preservation Tubes - Protocol (5 cc) - 50 tubes (18122) Urine Collection and Preservation Tubes - Protocol (15 cc) - 50 tubes (18113) Urine Collection and Preservation Tubes - Protocol (50 cc) - 50 tubes (18126) Urine Preservative Single Dose - Protocol (single dose) - 50 tubes (18129) Urine Collection and Preservation Cup - Protocol (120 cc cup) - 1 cup PRODUCT INFORMATION SHEETS Urine Preservation Product Information Sheet SAFETY DATA SHEETS Urine Preservation - Safety Data Sheet POSTERS Urine Preservation Sensitivity of DNA Extraction Methods From Different Bodily Fluids For Human Identification - Poster FLYERS Urine Collection and Preservation Flyer Citations Preservaton Tubes (18111, 18113, 18116, 18118, 18120, 18122, 18124, 18126) Title Urine PD-L1 is a tumor tissue candidate substitute and is associated with poor survival in muscle-invasive bladder cancer patients Journal International Immunopharmacology. 2023. Authors Jialu Ma, Quan Zhou, Wenbin Xu, Chuangui Li, Haicheng Wang, Zhao Zhai, Yong Zhang, Wasilijiang Wahafu Title Validation in an Independent Cohort of MiR-122, MiR-1271, and MiR-15b as Urinary Biomarkers for the Potential Early Diagnosis of Clear Cell Renal Cell Carcinoma Journal Cancers. 2022. Authors Giovanni Cochetti, Luigi Cari, Vincenza Maulà, Rosy Cagnani, Alessio Paladini, Michele Del Zingaro, Giuseppe Nocentini and Ettore Mearini Title Highly Sensitive and Specific Detection of Bladder Cancer via Targeted Ultra-deep Sequencing of Urinary DNA Journal European Urology Oncology 2022. Authors Douglas G. Ward, Laura Baxter, Sascha Ott, Naheema S.Gordon, Junhui Wang, Prashant Patel, Kim Piechocki, Lee Silcock, Chris Sale Title Automated DNA, RNA, and Protein Extraction from Urine for Biobanking Journal JBT 2022. Authors Pascale Maillé, Caroline Barau, Nanor Sirab, Bijan Ghaleh, and Yves Allory Title A Cost, Time, and Demographic Analysis of Participant Recruitment and Urine Sample Collection Through Social Media Optimization Journal The Journal of Urology 2022. Authors Prasun Sharma, Laura E. Lamb, Sarah N. Bartolone, Elijah P. Ward, Joseph J. Janicki, Kenneth M. Peters, Nitya Abraham, Melissa Laudano, Christopher P. Smith, Bernadette Zwaans, and Michael B. Chancellor Title Clinical features of chronic kidney disease in dogs with the serological presence of Leptospira spp, Ehrlichia canis and Anaplasma phagocytophilum Journal Research Square. 2022. Authors Claire A. Vázquez-Manzanilla, María F. Cárdenas-Marrufo, Eduardo Gutiérrez-Blanco, Matilde Jiménez-Coello, Nelly R. Pech-Sosa, Antonio Ortega-Pacheco Title Clinical Significance of Rab27a as a Urinary Biomarker in Patients With Bladder Cancer Journal KJUO. 2022. Authors Ja Yoon Ku, Eu Chang Hwang, Chan Ho Lee, Kyung Hwan Kim, Dong Deuk Kwon, Hong Koo Ha Title Molecular profiles and urinary biomarkers of upper tract urothelial carcinomas associated with aristolochic acid exposure Journal International Journal of Cancer 2021. Authors Sandra Karanović, Maude Ardin, Zuojian Tang, Karla Tomić, Stephanie Villar, Claire Renard, Elisa Venturini, Adam H. Lorch, Daniel S. Lee, Želimir Stipančić, Neda Slade, Ivana Vuković Brinar, Damir Dittrich, Krešimir Karlović, Fran Borovečki, Kathleen G. Dickman, Magali Olivier, Arthur P. Grollman, Bojan Jelaković, Jiri Zavadil Title Investigating the association between the urinary microbiome and bladder cancer: An exploratory study. Journal Urologic Oncology: Seminars and Original Investigations. Volume 39, Issue 6, 2021. Authors Hussein A, Elsayed A, Durrani M, et al. Title Methodology for the at-home collection of urine samples for prostate cancer detection Journal Biotechniques 68:65-71. 2020. Authors Martyn Webb , Kate Manley, Mireia Olivan, Ingrid Guldvik, Malgorzata Palczynska, Rachel Hurst, Shea P Connell, Ian G Mills, Daniel S Brewer, Robert Mills, Colin S Cooper & Jeremy Clark Title Integrated RNA and metabolite profiling of urine liquid biopsies for prostate cancer biomarker discovery. Journal Scientific Reports. Volume 10, Article: 3716. 2020. Authors Lee, B., Mahmud, I., Marchica, J. et al. Title Ascites-Derived Extracellular microRNAs as Potential Biomarkers for Ovarian Cancer Journal Reproductive Sciences. 2019. Authors Záveský, L., Jandáková, E., Weinberger, V. et al. Title Next Generation Sequencing of urine exfoliated cells: an approach of prostate cancer microRNAs research. Journal Scientific Reports. Volume 8, Article: 7111. 2018. Authors Guelfi, G., Cochetti, G., Stefanetti, V. et al. Title Cell-Free Urinary MicroRNAs Expression in Small-Scale Experiments Journal MicroRNA Detection and Target Identification. 2017 Authors Ludek Zavesky, Eva Jandakova, Radovan Turyna, Daniela Duskova, Lucie Langmeierova, Vit Weinberger, Lubos Minar, Ales Horinek, Milada Kohoutova Title Emerging Utility of Urinary Cell-free Nucleic Acid Biomarkers for Prostate, Bladder, and Renal Cancers Journal European Urology Focus. 2017 Authors Selena Y. Lin, Jennifer A. Linehan, Timothy G. Wilson, Dave S.B. Hoon Title A prospective multicenter study on bladder cancer: the COBLAnCE cohort Journal BMC Cancer. 2016. Authors Benhamou S, Bonastre J, Groussard K, Radvanyi F, Allory Y, Lebret T Title Supernatant versus exosomal urinary microRNAs. Two fractions with different outcomes in gynaecological cancers. Journal Neoplasma. 2015. Authors Zavesky L, Jandakova E, Turyna R, Langmeierova L, Weinberger V, Minar L Title Effects of hexanic extract of serenoa repens (permixon® 160 mg) on inflammation biomarkers in the treatment of lower urinary tract symptoms related to benign prostatic hyperplasia Journal The Prostate. 2015. Authors Alain Latil, Marie-Thérèse Pétrissans, Jérôme Rouquet, Grégoire Robert and Alexandre de la Taille Title Evaluation of Cell-Free Urine microRNAs Expression for the Use in Diagnosis of Ovarian and Endometrial Cancers. A Pilot Study Journal Pathology & Oncology Research. 2015. Authors Luděk Záveský, Eva Jandáková, Radovan Turyna, Lucie Langmeierová, Vít Weinberger, Lenka Záveská Drábková, Martina Hůlková, Aleš Hořínek, Daniela Dušková, Jaroslav Feyereisl, Luboš Minář, Milada Kohoutová Title Potential Urinary miRNA Biomarker Candidates for the Accurate Detection of Prostate Cancer among Benign Prostatic Hyperplasia Patients Journal Journal of Cancer. 2014. Authors Taha A Haj-Ahmad, Moemen AK Abdalla, Yousef Haj-Ahmad Title Potential Urinary Protein Biomarker Candidates for the Accurate Detection of Prostate Cancer among Benign Prostatic Hyperplasia Patients Journal Journal of Cancer. 2014. Authors Taha A Haj-Ahmad, Moemen AK Abdalla, Yousef Haj-Ahmad Preservaton Cup (18129) Title Using social media to crowdsource collection of urine samples during a national pandemic Journal International Urology and Nephrology. 2022 Authors Elijah P. Ward, Sarah N. Bartolone, Prasun Sharma, Michael B. Chancellor & Laura E. Lamb Title Cell-Free Urinary MicroRNAs Expression in Small-Scale Experiments Journal MicroRNA Detection and Target Identification. 2017 Authors Ludek Zavesky, Eva Jandakova, Radovan Turyna, Daniela Duskova, Lucie Langmeierova, Vit Weinberger, Lubos Minar, Ales Horinek, Milada Kohoutova Title Emerging Utility of Urinary Cell-free Nucleic Acid Biomarkers for Prostate, Bladder, and Renal Cancers Journal European Urology Focus. 2017 Authors Selena Y. Lin, Jennifer A. Linehan, Timothy G. Wilson, Dave S.B. Hoon Title A prospective multicenter study on bladder cancer: the COBLAnCE cohort Journal BMC Cancer. 2016. Authors Benhamou S, Bonastre J, Groussard K, Radvanyi F, Allory Y, Lebret T Title Supernatant versus exosomal urinary microRNAs. Two fractions with different outcomes in gynaecological cancers. Journal Neoplasma. 2015. Authors Zavesky L, Jandakova E, Turyna R, Langmeierova L, Weinberger V, Minar L Title Effects of hexanic extract of serenoa repens (permixon® 160 mg) on inflammation biomarkers in the treatment of lower urinary tract symptoms related to benign prostatic hyperplasia Journal The Prostate. 2015. Authors Alain Latil, Marie-Thérèse Pétrissans, Jérôme Rouquet, Grégoire Robert and Alexandre de la Taille Title Evaluation of Cell-Free Urine microRNAs Expression for the Use in Diagnosis of Ovarian and Endometrial Cancers. A Pilot Study Journal Pathology & Oncology Research. 2015. Authors Luděk Záveský, Eva Jandáková, Radovan Turyna, Lucie Langmeierová, Vít Weinberger, Lenka Záveská Drábková, Martina Hůlková, Aleš Hořínek, Daniela Dušková, Jaroslav Feyereisl, Luboš Minář, Milada Kohoutová Title Potential Urinary miRNA Biomarker Candidates for the Accurate Detection of Prostate Cancer among Benign Prostatic Hyperplasia Patients Journal Journal of Cancer. 2014. Authors Taha A Haj-Ahmad, Moemen AK Abdalla, Yousef Haj-Ahmad Title Potential Urinary Protein Biomarker Candidates for the Accurate Detection of Prostate Cancer among Benign Prostatic Hyperplasia Patients Journal Journal of Cancer. 2014. Authors Taha A Haj-Ahmad, Moemen AK Abdalla, Yousef Haj-Ahmad
Urine Collection and Preservation Devices For rapid and simple collection, and preservation of urine samples For research use only and NOT intended for in vitro diagnostics. Powered by Bioz Urine Collection and Preservation Devices For rapid and simple collection, and preservation of urine samples Price USD$525.00 SKU 18118 Format 5 cc 15 cc 50 cc Single Dose Preservative 120 cc Cup Size 50 Tubes Quantity Request sample