RNA Promotion

BIG SAVING

RNA

TOTAL RNA

EXTRACLEAN

EXOSOMES

DEAL - 1

Buy 2 kits, get 50% off on 3rd kit

Buy 2 RNA Products Get 3rd product 50% off*

DEAL - 2

Buy 4 kits, get 100% off on 5th kit

Buy 4 RNA Products Get 5th product free*

*Disclaimer: This promotion is available only to customers in Canada and the U.S. who place orders directly with Norgen Biotek. The discount is applied to the lowest-priced eligible product from selected RNA products. This offer cannot be combined with other existing promotions. Offer valid until Jan. 31st, 2025.

Products on Sale

  • All products

  • Total RNA

  • Exosomes

  • Extraclean

January Is The Total RNA Month

In addition to above offers, you can also get 100ml Ultrapure Nuclease-Free Water at 70% off when you buy any qualifying total RNA product

EXTRAClean Exosomal RNA Isolation Kit

72800

EXTRAClean Plasma/Serum Exosome Purification and RNA Isolation Mini Kit

73100

EXTRAClean RNA Clean-Up and Concentration Micro-Elute Kit

73600

EXTRAClean Plasma/Serum RNA Purification Mini Kit

73700

EXTRAClean Plasma/Serum Exosome and Free-Circulating RNA Isolation Mini Kit

73400

EXTRAClean Plasma/Serum RNA Purification Midi Kit

73710

EXTRAClean Plasma/Serum Exosome Purification and RNA Isolation Midi Kit

73110

EXTRAClean Plasma/Serum Exosome Purification and RNA Isolation Maxi Kit

73120

EXTRAClean Urine Exosome Purification and RNA Isolation Midi Kit

73200

EXTRAClean Urine Exosome Purification and RNA Isolation Mini Kit

73210

EXTRAClean Urine Exosome Purification and RNA Isolation Maxi Kit

73220

EXTRAClean Cell Culture Media Exosome Purification and RNA Isolation Mini Kit

73300

EXTRAClean Cell Culture Media Exosome Purification and RNA Isolation Midi Kit

73310

EXTRAClean Cell Culture Media Exosome Purification and RNA Isolation Maxi Kit

73320

EXTRAClean Plasma/Serum Exosome and Free-Circulating RNA Isolation Midi Kit

73410

EXTRAClean Plasma/Serum Exosome and Free-Circulating RNA Isolation Maxi Kit

73420

EXTRAClean Urine Exosome and Free-Circulating RNA Isolation Mini Kit

73500

EXTRAClean Urine Exosome and Free-Circulating RNA Isolation Midi Kit

73510

EXTRAClean Urine Exosome and Free-Circulating RNA Isolation Maxi Kit

73520

EXTRACleanPlasma/Serum RNA Purification Maxi Kit

73720

EXTRAClean Urine Cell-Free Circulating RNA Purification Mini Kit

73900

EXTRAClean Urine Cell-Free Circulating RNA Purification Midi Kit

73910

EXTRAClean Urine Cell-Free Circulating RNA Purification Maxi Kit

73920

Exosomal RNA Isolation Kit

58000

Plasma/Serum Exosome Purification Mini Kit

57400

Cell Culture Media Exosome Purification Mini Kit

60400

Plasma/Serum Exosome Purification and RNA Isolation Mini Kit

58300

Urine Exosome Purification Mini Kit

57700

Urine Exosome RNA Isolation Kit

47200

Urine Exosome Purification Midi Kit

57800

Cell Culture Media Exosome Purification Maxi Kit

60600

Plasma/Serum Exosome Purification and RNA Isolation Midi Kit

58500

Plasma/Serum Exosome Purification and RNA Isolation Maxi Kit

58600

Plasma/Serum Exosome Purification Midi Kit

57500

Plasma/Serum Exosome Purification Maxi Kit

57600

Plasma/Serum Exosome and Free-Circulating RNA Isolation Mini Kit

59500

FBS Exosome Depletion Kit I (Slurry Format)

61100

Urine Exosome Purification Maxi Kit

57900

Plasma/Serum Exosome and Free-Circulating RNA Isolation Maxi Kit

59700

Cell Culture Media Exosome Purification and RNA Isolation Mini Kit

60700

Saliva Exosome Purification Kit

65300

Exosome Labeling and Cleaning Kit

68400

Urine Exosome Purification and RNA Isolation Mini Kit

58400

Urine Exosome and Free-Circulating RNA Isolation Maxi Kit

59400

Plasma/Serum Exosome and Free-Circulating RNA Isolation Midi Kit

59600

Cell Culture Media Exosome Purification and RNA Isolation Midi Kit

60800

FBS Exosome Depletion Kit I (Column Format)

61200

FBS Exosome Depletion Kit II (Column Format)

61300

Saliva Exosome Collection and Preservation Kit

65400

Urine Exosome Purification and RNA Isolation Midi Kit

58700

Urine Exosome Purification and RNA Isolation Maxi Kit

58800

Urine Exosome and Free-Circulating RNA Isolation Mini Kit

59200

Urine Exosome and Free-Circulating RNA Isolation Midi Kit

59300

Cell Culture Media Exosome Purification and RNA Isolation Maxi Kit

60900

FBS Exosome Depletion Kit II (Slurry Format)

61400

Best-in-class RNA isolation technology driven by patented SiC matrix

Broad-spectrum RNA capture: total RNA including miRNA in one fraction

Sensitive & linear down to a few cells

Isolate from a wide variety of specimens

Fast processing time

Suitable for a variety of downstream applications

No Hassle

High Quality of Isolated RNA with Complete Size Range. Unlike most competitors' kits, Norgen's Total RNA Purification Kit allows for the isolation of all sizes of RNA, from the very large RNA down to the microRNA, without the use of phenol. Total RNA was isolated from 1 x 109 E. coli cells using Norgen’s Total RNA Purification Kit and a competitor’s kit. Five microliters and 1 µL of the 50 µL isolated RNA was analyzed on an agarose gel (Panel A) and the Agilent® 2100 BioAnalyzer RNA Nano 6000 chip (Panel B), respectively. Note the presence of small RNA species (red square) in the samples isolated via Norgen's kit and the absence of these RNA species in the competitor RNA preparation.

Great Isolation Sensitivity. Norgen's Total RNA Purification Kit allows sensitive RNA extraction from as little as a single cell. Total RNA was extracted from a decreasing number of 293 HEK cells from 1 million cells down to a single cell. Five microliters of the 50 µL isolated RNA was then subjected to a 20 µL reverse transcription using oligo dT primer. Three microliters of the reverse transcription was used in a 20 µL PCR reaction with primers to detect the human beta-actin transcripts. PCR products of beta-actin were detected from as little as a single cell. M is the marker lane.

High Quality of RNA from a Diverse Range of Inputs. Norgen's Total RNA Purification 96-Well Kit allows for RNA isolation from a wide range of species and tissue types. Total RNA was isolated from 8 mg of brain (Lanes A), kidney (Lanes B), liver (Lanes C), lung (Lanes D) and spleen tissue (Lanes E), 7.5 x 105 HeLa (Lanes F) and CHO cells (Lanes G), and 5 x 108 bacteria (Lanes H) using Norgen's Total RNA Purification 96-Well Kit. Five microliters of the 75 µL isolated RNA were resolved on a 1.2% formaldehyde agarose gel. From observing the formaldehyde-agarose gel, it can be seen that Norgen's kit can be used to successfully isolate total RNA, including small RNA species, from a broad range of sample types.

Services

  • RNA Sequencing
  • Small RNA sequencing
  • PCR/qPCR
  • Microarray
Explore More

Norgen’s patented SiC matrix ensures:

  • Need for inhibitor like Phenol-chloroform
  • Bias towards high molecular weight
  • Bias towards high GC content
  • Need for carrier RNA
  • Loss of RNA diversity

Quick and easy protocol for the purification of exosome from a range of sample volumes

Purification and enrichment of intact exosomes from various liquid biopsy sample types

No Precipitation reagents, overnight incubation, protease or coagulant treatments required

Ready in 30 Minutes

Purified exosomes are free from any RNA-binding proteins

NanoSight data showing intact exosomes purified from 1 mL and 10 mL plasma Intact exosomes were purified from 1 mL plasma using Norgen's Plasma/Serum Exosome Purification Mini Kit (Cat. 57400) and from 10 mL plasma using Norgen's Plasma/Serum Exosome Purification Maxi Kit (Cat. 57600). Exosomes purified using Norgen's Mini kit were resuspended in 200 µL of Norgen's ExoR buffer whereas exosomes purified using Norgen's Maxi kit were resuspended in 600 µL Norgen's ExoR buffer, diluted 1:1,000 and visualized on the NanoSight LM10 instrument. The analysis shows that the purification of exosomes is linear as 4.04 x 1010 particles/mL was recovered from 1 mL plasma whereas 2.95 x 1011 particles/mL was recovered from 10 mL plasma.

TEM images of small EVs obtained from the same non disease frozen platelet free plasma (ND-frozen PFP) sample. Sample isolated with three commercial kits; representatives of >10 images are shown (scale bar, 200 nm).

Purify small RNA with minimal background noise for enhanced sequencing results

Enhanced microRNA reads in small RNA NGS

Reduce the number of unmapped reads

Optimized for exosomal RNA and cell-free RNA from low input samples.

Potential to reduce sequencing costs significantly

Average small RNA biotype distribution relative to the input reads obtained from sequencing of exosomal RNA extracted from various plasma and serum using EXTRAClean Plasma/Serum Exosome Purification and RNA Isolation Maxi Kit.

Genome mapping distribution relative to input reads obtained from small RNA sequencing of exosomal RNA extracted from various plasma and serum samples using EXTRAClean Plasma/Serum Exosome Purification and RNA Isolation Maxi Kit.

Average read quality distribution relative to raw reads of small RNA sequencing of exosomal RNA extracted from various urine volumes using EXTRAClean Urine Exosome Purification and RNA Isolation Maxi Kit. Calculations were relative to raw reads.

Average small RNA biotype distribution relative to the input reads obtained from sequencing of exosomal RNA extracted from various plasma and serum using EXTRAClean Plasma/Serum Exosome Purification and RNA Isolation Maxi Kit.

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