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saliva collection device

COLLECTION

ISOLATION

DETECTION

1 Sample Collection & Preservation

Saliva RNA Collection & Preservation Device

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Saliva RNA Collection & Preservation Device

Norgen's Saliva RNA Collection and Preservation Devices Dx are designed for 1) safe and non-invasive saliva collection and 2) preservation of RNA in saliva samples at ambient temperature. Each of the 50 Saliva RNA Collection and Preservation Devices Dx consists of 3 components: (1) Saliva Collection Funnel and Collection Tube, (2) Collection Tube Cap, and (3) Norgen's Saliva RNA Preservative contained within a sealed squeezable ampoule. Saliva samples are collected by spitting inside the Collection Funnel which has been assembled with the Collection Tube. After collecting the required volume of saliva the Collection Funnel is removed and the contents of the Preservative Ampoule are then added and mixed with the collected saliva. The Saliva Collection Tube is subsequently sent to the laboratory for RNA isolation and analysis. RNA can be isolated from the preserved saliva samples using Norgen's Saliva/Swab RNA Purification Kits Dx (Cat# 69100/69300). Each of Norgen's Collection Tubes is labeled with a unique serial number that can be used for secure and anonymous tracking of the sample. The saliva RNA in preserved samples is stable for up to 2 months at room temperature. This kit is ideal for collecting and preserving RNA samples for in vitro diagnostic use for medical purposes.

  • Non-invasive collection procedure — just spit, twist, test
  • Viral inactivation for safe transport & handling
  • Tested on SARS-CoV-2 virus
  • Inactivates virus within 5 minutes of mixing
  • CE-IVD marked version available
  • Authorized for sale by Health Canada
  • Suitable for self-collection of saliva samples supervised by a trained individual in the collection procedure by watching the training video and reading over the collection instructions.

Total Nucleic Acid Preservation Tubes

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Total Nucleic Acid Preservation Tubes

Norgen's Total Nucleic Acid Preservation Tubes Dx are designed for ambient preservation and transport of total nucleic acids (DNA and RNA) from samples collected using a swab. The Total Nucleic Acid Preservation Tubes contain Norgen's Total Nucleic Acid Preservative in a liquid format. The user simply collects the specimen using a sterile nylon flocked swab (not provided), and then transfers the swab into the Total Nucleic Acid Preservative. The Preservative prevents the growth of Gram-negative and Gram-positive bacteria and fungi, and also inactivates viruses allowing the resulting non-infectious samples to be handled and shipped safely. In addition, the Total Nucleic Acid Preservative eliminates the need to immediately process or freeze samples and allows the samples to be shipped to centralized testing facilities at ambient temperatures. The components of the preservative allow DNA samples to be stored at room temperature for over 4 months and RNA samples to be stored at room temperature for over 2 months. This kit is ideal for collecting and preserving nasal and oral swab samples for in vitro diagnostic use for medical purposes. Norgen's Total Nucleic Acid Preservation Tubes Dx are intended for use by professional users such as technicians, physicians and biologists experienced and trained in molecular biological techniques. Norgen's Total Nucleic Acid Preservation Tubes Dx do not provide a diagnostic result. It is the sole responsibility of the user to use and validate these devices in conjunction with a downstream in vitro diagnostic assay.

  • No need to immediately process samples
  • Total DNA, including viral DNA, preserved at room temperature over 4 months
  • Total RNA, including viral RNA, preserved at room temperature over 2 months
  • Inactivate microorganisms including bacteria, fungi, yeast and viruses
  • Ship swab samples at room temperature safely
  • Compatible with most DNA and Viral RNA isolation methods
  • CE-IVD marked version available
  • Authorized for sale by Health Canada

2 Viral RNA Isolation

Saliva/Swab RNA Purification Kits

Saliva/Swab RNA Purification Kits

Norgen's Saliva/Swab RNA Purification Kit provides a rapid method for the purification of total RNA from non-preserved saliva and nasal/throat swabs, and from preserved saliva collected on Norgen's Saliva RNA Collection and Preservation Devices (Cat. RU53800) or preserved swabs collected in Norgen's Total Nucleic Acid Preservative Tubes (Cat. 69200). Purification is based on using Norgen's proprietary resin separation matrix. RNA is preferentially purified from other cellular components such as proteins, without the use of phenol or chloroform. The kit allows the purification of total RNA, including viral and bacterial RNA, irrespective of size or GC content. The purified RNA is eluted in an Elution Solution that is compatible with all downstream applications including PCR, qPCR, methylation-sensitive PCR and Southern Blot analysis, microarrays, and NGS.

  • Isolate high quality total RNA, including viral RNA, from fresh and preserved saliva and swab samples
  • Fast and easy processing using rapid spin-column format
  • Isolate total RNA, from large rRNA down to microRNA (miRNA)
  • No phenol or chloroform extractions
  • Very sensitive & linear down to a few cells/viral copies without the need for carrier RNA
  • Buffer chemistry inactivates viruses including SARS-CoV-2
  • High throughput 96-well plate format for rapid purifications is also available
  • Purification is based on spin column chromatography that uses Norgen’s proprietary resin separation matrix
  • Authorized for sale by Health Canada
  • CE-IVD marked version available

Total RNA Purification Kits

Total RNA Purification Kit

Norgen's Total RNA Purification Kit Dx provides a rapid method for the isolation and purification of total RNA from tissue samples, blood, plasma, serum, saliva, bacteria, yeast, fungi and viruses for subsequent in vitro diagnostic use.

This kit is designed to be used with any downstream application employing enzymatic amplification or other enzymatic modifications of RNA followed by signal detection or amplification. Extract high quality and purity RNA with excellent RIN values and A260/A280 suitable for downstream applications including qRT-PCR, RT-PCR, microarrays, NGS and more. Any diagnostic results generated using the RNA isolated with Norgen's Total RNA Purification Kit Dx in conjunction with an in vitro diagnostic assay should be interpreted with regard to other clinical or laboratory findings.

  • Extract high quality & purity total RNA including miRNA
  • No phenol step required
  • Bind & elute all RNA irrespective of size or GC content, without bias
  • Very sensitive & linear down to a few cells without the need for carrier RNA
  • Convenient & fast spin column format
  • Isolate from a wide variety of specimens
  • Purified RNA is suitable for a variety of downstream applications
  • Buffer chemistry inactivates viruses including SARS-CoV-2
  • Purification is based on spin column chromatography that uses Norgen’s proprietary resin separation matrix
  • Authorized for sale by Health Canada
  • CE-IVD marked version available