Intact Exosome Purification
- Purification and enrichment of intact exosomes from plasma, serum, urine, cell culture media and saliva in less than 30 minutes.
- Exosome purification is based on Norgen’s proprietary resin separating matrix through exosomes’ surface proteins.
- No precipitation reagents, overnight incubation, protease or coagulant treatments required
- No time-consuming ultracentrifugation, filtration or special syringes required
- Purify intact exosomes with a size ranging from 40-200 nm depending on sample input type
- Purified exosomes are compatible with functional studies.
- Purified exosomes are free from any protein-bound cell-free circulating RNA
- Purified exosomes are compatible with NanoSight® or Electron Microscopy for assessing the approximate exosome size range and concentration.
- Exosomal RNA can be extracted from the purified exosomes using Norgen’s Exosomal RNA Purification technology or any other RNA extraction method.
Exosomes: The Essentials
Kits for Research Use
| Cat. # | Name | Size | |
|---|---|---|---|
| 57400, 57500, 57600 | Plasma/Serum Exosome Purification Kits | 50 preps, 25 preps, 15 preps | View product page |
| 57700, 57800, 57900 | Urine Exosome Purification Kits | 50 preps, 25 preps, 15 preps | View product page |
| 60400, 60600 | Cell Culture Media Exosome Purification Kits | 50 preps, 15 preps | View product page |
| 65300 | Saliva Exosome Purification Kit | 50 preps | View product page |
Purify intact, functional extracellular vesicles including exosomes
Norgen’s Exosome Purification Kits enable fast, flexible, robust, and convenient intact exosome purification from a wide range of cell-free liquid biopsies and cell-free cell culture media. Relying on Norgen’s proprietary resin technology, the intact exosomes are purified in 30 minutes and are free from any cell-free circulating protein-bound RNA which typically contaminates exosomes and impedes effective exosomal content analyses. Norgen’s intact exosome purification methodology does not involve any troublesome and tedious ultracentrifugation, any chemical or immuno-precipitation techniques, any protease or coagulant treatments and doesn’t require any special equipment or overnight incubation. The purified intact exosomes are amenable to labelling, counting, imaging, and in vivo / in vitro functional studies, as well as exosomal analyte isolations and analyses.
