Note: This product is not available for sale in the United States

For Whole Blood Collection and Preservation of Cell-Free Circulating DNA and RNA

  • CE-IVD marked in accordance with EU Directive 98/79/EC
  • Ideal for use in in vitro diagnostic workflows
  • Fixative-free preservative, no cross-linking of DNA
  • Preserve cf-DNA/ct-DNA for 30 days at ambient temperature and for up to 8 days at 37°C.
  • Preserve cf-RNA for 30 days at ambient temperature
  • Preserve Circulating Tumour Cells (CTCs) for 14 days at ambient temperature
  • No plasma volume loss after shipping/transportation
  • Prevent hemolysis allowing better separation of plasma
  • Prevent apoptosis of blood cells and fragmentation of genomic DNA
  • Produce high quality/quantity of plasma cf-DNA/ct-DNA/cf-RNA
  • Vacuumed to draw 8.4 mL of blood in 10 mL tubes

ItemsCat. #Size
cf-DNA/cf-RNA Preservative Tubes Dx Dx63950 50 tubes

cf-DNA/cf-RNA Preservative Tubes Dx

Norgen's cf-DNA/cf-RNA Preservative Tubes Dx are closed, evacuated plastic tubes for the collection and the preservation of cf-DNA, circulating tumor DNA, cf-RNA and circulating tumor cells in human whole blood samples during storage and shipping. Using these tubes in combination with Norgen's Plasma/Serum Cell-Free Circulating DNA Purification Kits or Norgen's Plasma/Serum RNA Purification Kits enables the purification and concentration of an inhibitor-free cf-DNA/ct-DNA/cf-RNA in a very small elution volume.

These tubes are ideal for collecting and preserving cf-DNA and cf-RNA samples for in vitro diagnostic use for medical purposes.

Performance

Norgen's cf-DNA/cf-RNA Preservative Tubes Dx abridge the collection/processing of whole blood for the subsequent purification of cf-DNA and/or cf-RNA. The cf-DNA/cf-RNA Preservative Tubes Dx preserve and inhibit the programmed cell-death (apoptosis) of the blood, hence preventing the release of intracellular DNA/RNA into plasma. Whole blood samples can be shipped and stored at room temperature for the subsequent processing of plasma. The cf/ct DNA and cf-RNA levels are stable for up to 30 days at room temperature. The cf-DNA is also stable for up to 8 days at 37°C.

Workflow

Collection and Mixing Instructions

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NOTE: This product is not available for sale in the United States. For the research use only version, see Cat. 63950

Kit Specifications
Tube Size
16 x 100 mm
Tube Type PET Tube
Blood Draw Volume
8.4 mL in 10 mL Tubes
Preservative Volume
1.6 mL
Recovered Plasma Volume Approximately 6-7 mL
(not affected by shipping)
Anticoagulant
Proprietary
Preservative
Non formaldehyde - Proprietary preservation agent

Length of cf-DNA Preservation

Up to 30 days at room temperature (15-25°C)
Up to 8 days at 37°C

Length of cf-RNA Preservation

Up to 30 days at room temperature (15-25°C)

Length of CTCs Preservation

Up to 14 days at room temperature (15-25°C)

Storage Conditions and Product Stability

  1. When stored at 15-30°C, unfilled Norgen cf-DNA/cf-RNA Preservative Tubes Dx are stable through the expiration date. See tube label for expiry date.
  2. Short-term storage/shipping at -20°C to 37°C for up to 10 days is acceptable for unfilled Norgen cf-DNA/cf-RNA Preservative Tubes Dx.
  3. Do not freeze unfilled Norgen cf-DNA/cf-RNA Preservative Tubes Dx for long term storage over 10 days. Freezing unfilled tubes may lead to loss of vacuum and precipitation may occur.
  4. Cell-free DNA in blood samples collected in Norgen's cf-DNA/cf-RNA Preservative Tubes Dx is stable for up to 30 days when stored at room temperature (15-25°C)
  5. Cell-free DNA in blood samples collected in Norgen's cf-DNA/cf-RNA Preservative Tubes Dx is stable for up to 8 days when stored at 37ºC.
  6. Cell-free RNA in blood samples collected in Norgen's cf-DNA/cf-RNA Preservative Tubes Dx is stable for up to 30 days when stored at room temperature (15-25°C)
  7. Circulating tumor cells (CTCs) in blood samples collected in Norgen's cf-DNA/cf-RNA Preservative Tubes Dx are stable for up to 14 days at room temperature (15-25ºC).


Kit Components
Component Cat. Dx63950 (50 tubes)
cf-DNA/cf-RNA Preservative Tubes Dx 50
Product Insert 1