For the rapid and efficient purification, cleanup and concentration of RNA or DNA

  • Can be used for the clean up of both RNA and DNA from enzymatic reactions, labeling etc.
  • Purifies all sizes of RNA, from large mRNA down to microRNA (miRNA) 
  • Purifies all sizes of DNA, from small PCR products to plasmids to genomic DNA
  • Removes endotoxins for transfection of injection ready RNA or DNA
  • Rapid and efficient spin-column format (20 minutes)

ItemsCat. #Size
CleanAll DNA/RNA Clean-Up and Concentration Micro Kit 23800 50 preps

CleanAll DNA/RNA Clean-Up and Concentration Micro Kit

Norgen's CleanAll DNA/RNA Clean-Up and Concentration Micro Kit provides a rapid method for the purification, cleanup and concentration of RNA or DNA from different isolation methods or upstream applications.   The kit can be used as an alternative to organic extraction and ethanol precipitation to clean up various enzymatic reactions. 

The CleanAll Kit purifies RNA from phenol/guanidine-based protocols or from various upstream enzymatic reactions such as DNase treatment, labeling and in vitro transcription. Furthermore, endotoxins can be removed from previously purified RNA solutions.

The kit can be used to clean up DNA from digestions, ligations, PCR reactions, labeling reactions, DNA modification reactions and staining. The kit also provides a protocol for the rapid removal of endotoxins from previously purified DNA down to 0.1 EU/µg DNA or less.

Purify all sizes of RNA, from large mRNA and ribosomal RNA down to microRNA (miRNA) and small interfering RNA (siRNA).

Purify all sizes of DNA, from small PCR products, native or linearized plasmids, to genomic DNA. Using an alternative protocol, even oligonucleotides and smaller DNA fragments can be purified.

Kit Specifications
Column Binding Capacity
50 μg RNA
10 μg DNA
Maximum Column Loading Volume
600 μL
Minimum Elution Volume
20 μL
Time to Complete 10 Purifications
20 minutes
Size of RNA Purified
All sizes, including small RNA (<200)
Size of DNA Purified
≥ 100 bp*
Average Recovery
≥90% for RNA
≥90% for DNA 100 bp to 10 kbp
≥75% for DNA ≥ 10 kbp

* Applicable to smaller fragments or oligonucleotides with alternative protocol

Storage Conditions and Product Stability
All solutions should be kept tightly sealed and stored at room temperature.  These reagents should remain stable for at least 1 year in their unopened containers.

Title Microbial N transformations and N2O emission after simulated grassland cultivation: Effects of the nitrification inhibitor 3,4-dimethylpyrazole phosphate (DMPP)
Journal Applied and Environmental Microbiology. 2016.
Authors Duan YF, Kong XW, Schramm A, Labouriau R, Eriksen J, Petersen SO.
Title 3,4-Dimethylpyrazole phosphate (DMPP) reduces activity of ammonia oxidizers without adverse effects on non-target soil microorganisms and functions
Journal Applied Soil Ecology. 2016.
Authors Kong, X., Duan, Y., Schramm, A., Eriksen, J., & Petersen, S. O.
Title Bioengineering Novel Chimeric microRNA-34a for Prodrug Cancer Therapy: High-Yield Expression and Purification, and Structural and Functional Characterization
Journal Journal of Pharmacology and Experimental Therapeutics. 2015.
Authors Wang WP, Ho PY, Chen QX, Addepalli B, Limbach PA, Li MM, Wu WJ, Jilek JL, Qiu JX, Zhang HJ, Li T, Wun T, White RD, Lam KS, Yu AM
Title A modular method for the extraction of DNA and RNA, and the separation of DNA pools from diverse environmental sample types
Journal Frontiers in Microbiology. 2015.
Authors Mark Alexander Lever, Andrea Torti, Philip Eickenbusch, Alexander Bryce Michaud, Tina Šantl-Temkiv and Bo Barker Jørgensen
Title Establishment of a minigenome system for Oropouche orthobunyavirus reveals the S genome segment to be significantly longer than previously reported
Journal Journal of General Virology. 2014.
Authors Gustavo Olszanski Acrani1, Natasha L Tilston-Lunel2, Martin Spiegel3, Manfred Weidemann4, Meik Dilcher5, Daisy Elaine Andrade da Silva6, Marcio R.T. Nunes7 and Richard M. Elliott
Title Site-and horizon-specific patterns of microbial community structure and enzyme activities in permafrost-affected soils of Greenland.
Journal Frontiers in Microbiology. 2014.
Authors Antje Gittel, Jiri Barta, Iva Lacmanova, Joerg Schnecker, Birgit Wild, Petr Capek, Christina Kaiser, Vigdis Torsvik, Andreas Richter, Christa Schleper and Tim Urich.
Title Distinct microbial communities associated with buried soils in the Siberian tundra.
Journal RNA Biology. 2013.
Authors Gittel A, Bárta J, Kohoutová I, Mikutta R, Owens S, Gilbert J, Schnecker J, Wild B, Hannisdal B, Maerz 8, Lashchinskiy N, Capek P, Santrucková H, Gentsch N, Shibistova O, Guggenberger G, Richter A, Torsvik VL, Schleper C, Urich T.
Title Genetic characterization of Erve virus, a European Nairovirus distantly related to Crimean-Congo hemorrhagic fever virus.
Journal Virus Genes. 2012.
Authors Dilcher M, Koch A, Hasib L, Dobler G, Hufert FT, Weidmann M.
Title Placental Expression of CD100, CD72 and CD45 Is Dysregulated in Human Miscarriage.
Journal PLOS One. 2012.
Authors Lorenzi T, Turi A, Lorenzi M, Paolinelli F, Mancioli F Sala L, Morroni M, Ciarmela P, Mantovani A, Tranquilli A, Castellucci M, Marzioni D.
Title Effect of DNA Contaminants on Calcium Phosphate-Based DNA Delivery and Gene Expression.
Journal Journal of Biotech Research. 2012.
Authors El-Mogy M and Haj-Ahmad Y.
Title Epigenetic Differences in Normal Colon Mucosa of Cancer Patients Suggest Altered Dietary Metabolic Pathways.
Journal Cancer Preventation Research. Philidelphia (PA). 2012.
Authors Silviera ML, Smith BP, Powell J, Sapienza C.