Have a product in mind? Ask the experts! Request a Quote
For the convenient purification of cytoplasmic and nuclear RNA from cultured cells and tissues
Items | Cat. # | Size | |
---|---|---|---|
Cytoplasmic & Nuclear RNA Purification Kit | 21000 | 50 preps | |
Cytoplasmic & Nuclear RNA Purification Kit | 37400 | 100 preps |
Cytoplasmic and Nuclear RNA Purification Kit
This kit provides a rapid method for the isolation and purification of both cytoplasmic and nuclear RNA from cultured animal cells and small tissue samples. The kit can be used to isolate all sizes of RNA from the cytoplasmic and nuclear RNA fractions, including all small RNA species without any requirement for phenol. Included in the kit are sufficient reagents to perform either 50 cytoplasmic RNA preparations or 25 cytoplasmic and 25 nuclear RNA preparations. Ten samples can be processed in approximately 45 minutes. This kit is also available in a 100 prep size.
Background
In certain circumstances it is desirable to be able to isolate fractionated RNA as opposed to total RNA. For example, it may be preferable to isolate only mature, cytoplasmic RNA for some studies on expression profiling. Alternatively it may be desirable to isolate nuclear RNA in order to investigate and study pre-processed (non-spliced) RNA. Furthermore, this kit can be used to isolate RNA for downstream applications where it is necessary to avoid DNA contamination, since the cytoplasmic fraction has been shown to be free of all traces of genomic DNA.
Kit Specifications
|
|
Maximum Column Binding Capacity
|
Up to 50 µg RNA
|
Maximum Column Loading Volume
|
650 µL
|
Size of RNA Purified
|
All sizes, including small RNA (< 200 nt)
|
Time to Complete 10 Purifications |
45 minutes
|
RNA Yield
HeLa (1 x 106) - Cytoplasmic RNA HeLa (1 x 106) - Nuclear RNA |
15 µg
≤ 3.5 µg |
Storage Conditions and Product Stability
All solutions should be kept tightly sealed and stored at room temperature. These reagents should remain stable for at least 1 year in their unopened containers.
Title | C-MYC-induced upregulation of lncRNA SNHG12 regulates cell proliferation, apoptosis and migration in triple-negative breast cancer |
Journal | Am J Transl Res. 2017 |
Authors | Ouchen Wang, Fan Yang, Yehuan Liu, Lin Lv, Ruimin Ma, Chuanzhi Chen, Jiao Wang, Qiufan Tan,Yue Cheng, Erjie Xia, Yizuo Chen, Xiaohua Zhang |
Title | Long noncoding RNA MHENCR promotes melanoma progression via regulating miR-425/489-mediated PI3K-Akt pathway |
Journal | American Journal of Translational Research. 2017. |
Authors | Chen X, Dong H, Liu S, Yu L, Yan D, Yao X, Sun W, Han D, Gao G. |
Title | Neuronal hemoglobin affects dopaminergic cells’ response to stress |
Journal | Cell Death and Disease. 2017. |
Authors | Codrich M, Bertuzzi M, Russo R, Francescatto M, Espinoza S, Zentilin L, Giacca M, Cesselli D, Beltrami AP, Ascenzi P, Zucchelli S,, Persichetti F, Leanza G, Gustincich S |
Title | Satellite RNAs promote pancreatic oncogenic processes via the dysfunction of YBX1 |
Journal | Nature Communications. 2016. |
Authors | Kishikawa T, Otsuka M,, Yoshikawa T, Ohno M, Ijichi H, Koike K. |
Title | Extracellular Vesicles Including Exosomes Regulate Innate Immune Responses to Hepatitis B Virus Infection |
Journal | Frontiers in Immunology. 2016. |
Authors | Kouwaki T, Fukushima Y, Daito T, Sanada T, Yamamoto N, Mifsud EJ, Leong CR, Tsukiyama-Kohara K, Kohara M, Matsumoto M, Seya T, Oshiumi H |
Title | Evidence for a role of a lncRNA encoded from the p53 tumor suppressor gene in maintaining the undifferentiated state of human myeloid leukemias |
Journal | Gene Reports. 2016. |
Authors | Reisman, D., Gibson, A., Patel, M., & Wang, Y |
Title | The microRNA cluster miR-183/96/182 contributes to long-term memory in a protein phosphatase 1-dependent manner |
Journal | Nature Communications. 2016. |
Authors | Woldemichael BT, Jawaid A, Kremer EA, Gaur N, Krol J, Marchais A, Mansuy IM |
Title | Long noncoding RNA GPC3-AS1 promotes hepatocellular carcinoma progression via epigenetically activating GPC3 |
Journal | The FEBS Journal. 2016. |
Authors | Zhu XT, Yuan JH, Zhu TT, Li YY, Cheng XY |
Title | Global transcript structure resolution of high gene density genomes through multi-platform data integration |
Journal | Nucleic Acids Research. 2016. |
Authors | O'Grady T, Wang X, Höner Zu Bentrup K, Baddoo M, Concha M, Flemington EK |
Title | Long noncoding RNA GIHCG promotes hepatocellular carcinoma progression through epigenetically regulating miR-200b/a/429 |
Journal | Journal of Molecular Medicine. 2016. |
Authors | Sui CJ, Zhou YM, Shen WF, Dai BH, Lu JJ, Zhang MF, Yang JM |
Title | miR-34 activity is modulated through 5′-end phosphorylation in response to DNA damage |
Journal | Nature Communications. 2016. |
Authors | Salzman DW, Nakamura K, Nallur S, Dookwah MT, Metheetrairut C, Slack FJ, Weidhaas JB |
Title | Long noncoding RNA FGFR3-AS1 promotes osteosarcoma growth through regulating its natural antisense transcript FGFR3 |
Journal | Molecular Biology Reports. 2016. |
Authors | Sun, J., Wang, X., Fu, C., Wang, X., Zou, J., Hua, H., & Bi, Z. |
Title | Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism |
Journal | Nature. 2015. |
Authors | Derek A. Oldridge, Andrew C. Wood, Nina Weichert-Leahey, Ian Crimmins, Robyn Sussman, Cynthia Winter, Lee D. McDaniel, Maura Diamond, Lori S. Hart, Shizhen Zhu, Adam D. Durbin, Brian J. Abraham, Lars Anders, Lifeng Tian, Shile Zhang, Jun S. Wei, Javed Khan, Kelli Bramlett, Nazneen Rahman, Mario Capasso, Achille Iolascon, Daniela S. Gerhard, Jaime M. Guidry Auvil, Richard A. Young, Hakon Hakonarson et al. |
Title | Long Non-coding RNA Growth Arrest-specific Transcript 5 (GAS5) Inhibits Liver Fibrogenesis through a Mechanism of Competing Endogenous RNA |
Journal | The Journal of Biological Chemistry. 2015. |
Authors | Fujun Yu, Jianjian Zheng, Yuqing Mao, Peihong Dong, Zhongqiu Lu, Guojun Li, Chuanyong Guo, Zhanju Liu and Xiaoming Fan |
Title | The Role of Long Intergenic Noncoding RNA p21 in Vascular Endothelial Cells |
Journal | DNA and Cell Biology. 2015. |
Authors | He C, Ding JW, Li S, Wu H, Jiang YR, Yang W, Teng L, Yang J, Yang J |
Title | Regulation of p53 during senescence in normal human keratinocytes |
Journal | Aging Cell. 2015. |
Authors | Kim RH, Kang MK, Kim T, Yang P, Bae S, Williams DW, Phung S, Shin KH, Hong C, Park NH |
Title | New non-coding lytic transcripts derived from the Epstein Barr virus latency origin of replication oriP are hyper-edited, bind the paraspeckle protein, NONO/p54nrb, and support lytic viral transcription. |
Journal | Journal of Virology. 2015. |
Authors | Cao S, Moss W, O'Grady T, Concha M, Strong MJ, Wang X, Yu Y, Baddoo M, Zhang K, Fewell C, Lin Z, Dong Y, Flemington EK |
Title | A lncRNA regulates alternative splicing via establishment of a splicing-specific chromatin signature |
Journal | Nature Structural & Molecular Biology. 2015. |
Authors | Inma Gonzalez, Roberto Munita, Eneritz Agirre, Travis A Dittmer, Katia Gysling, Tom Misteli & Reini F Luco |
Title | Microtubule disruption synergizes with oncolytic virotherapy by inhibiting interferon translation and potentiating bystander killing. |
Journal | Nature Communications. 2015. |
Authors | Rozanne Arulanandam, Cory Batenchuk, Oliver Varette, Chadi Zakaria, Vanessa Garcia, Nicole E. Forbes, Colin Davis, Ramya Krishnan, Raunak Karmacharya, Julie Cox, Anisha Sinha, Andrew Babawy, KatherineWaite, EricaWeinstein, Theresa Falls, Andrew Chen, Jeff Hamill, Naomi De Silva, David P. Conrad, Harold Atkins, Kenneth Garson, Carolina Ilkow, Mads Kærn, Barbara Vanderhyden, Nahum Sonenberg, Tommy Alain, Fabrice Le Boeuf, John C. Bell1, & Jean-Simon Diallo |
Title | SP1-induced upregulation of the long noncoding RNA TINCR regulates cell proliferation and apoptosis by affecting KLF2 mRNA stability in gastric cancer. |
Journal | Oncogene. 2015. |
Authors | Xu TP, Liu XX, Xia R, Yin L, Kong R, Chen WM, Huang MD, Shu YQ. |
Title | Developmental regulation of human cortex transcription and its clinical relevance at single base resolution. |
Journal | Nature Neuroscience. 2014. |
Authors | Andrew E Jaffe, Jooheon Shin, Leonardo Collado-Torres, Jeffrey T Leek, Ran Tao, Chao Li, Yuan Gao, Yankai Jia, Brady J Maher, Thomas M Hyde, Joel E Kleinman & Daniel R Weinberger. |
Title | High-Throughput RNA sequencing based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia project. |
Journal | Journal of Virology. 2014. |
Authors | Cao S, Strong MJ, Wang X, Moss WN, Concha M, Lin Z, O'Grady T, Baddoo M, Fewell C, Renne R, Flemington EK. |
Title | Long Noncoding RNA-EBIC Promotes Tumor Cell Invasion by Binding to EZH2 and Repressing E-Cadherin in Cervical Cancer. |
Journal | PLoS ONE. 2014. |
Authors | Ning-xia Sun, Chen Ye, Qian Zhao, Qing Zhang, Chen Xu, Shao-bing Wang, Zhi-jun Jin, Shu-han Sun, Fang Wang, Wen Li mail |
Title | Dramatic Increase in Expression of a Transgene by Insertion of Promoters Downstream of the Cargo Gene. |
Journal | Molecular Biotechnology. 2014. |
Authors | Sakaguchi M, Watanabe M, Kinoshita R, Kaku H, Ueki H, Futami J, Murata H, Inoue Y, Li SA, Huang P, Putranto EW, Ruma IM, Nasu Y, Kumon H, Huh NH. |
Title | Strain-level genomic variation in natural populations of Lebetimonas from an erupting deep-sea volcano. |
Journal | Journal of Virology. 2013. |
Authors | O'Grady T, Cao S, Strong MJ, Concha M, Wang X, Bondurant SS, Adams M, Baddoo M, Srivastav SK, Lin Z, Fewell C, Yin Q, Flemington EK. |
Title | Efficient cellular fractionation improves RNA sequencing analysis of mature and nascent transcripts from human tissues. |
Journal | BMC Biotechnology. 2013. |
Authors | Zaghlool A, Ameur A, Nyberg L, Halvardson J, Grabherr M, Cavelier L, Feuk L. |
Title | Dengue virus subgenomic RNA induces apoptosis through the Bcl-2-mediated PI3k/Akt signaling pathway. |
Journal | Virology. 2013. |
Authors | Liua Y, Liua H, Zoua J, Zhanga B and Yuana Z |
Title | Identification of a long non-coding RNA-associated RNP complex regulating metastasis at the translational step |
Journal | The EMBO Journal. 2013. |
Authors | Gumireddy K, Li A, Yan J, Setoyama T, Johannes GJ, Orom UA, Tchou J, Liu Q, Zhang L, Speicher DW, Calin GA, Huang Q. |
Title | MiR-138 downregulates miRNA processing in HeLa cells by targeting RMND5A and decreasing Exportin-5 stability. |
Journal | Nucleic Acids Research. 2013. |
Authors | Li J, Chen Y, Qin X, Wen J, Ding H, Xia W, Li S, Su X, Wang W, Li H, Zhao Q, Fang T, Qu L, Shao N. |
Title | Zinc-finger antiviral protein mediates retinoic acid inducible gene I-like receptor-independent antiviral response to murine leukemia virus. |
Journal | Proceedings of the National Academy of Sciences of the United States of America. 2013. |
Authors | Lee H, Komano J, Saitoh Y, Yamaoka S, Kozaki T, Misawa T, Takahama M, Satoh T, Takeuchi O, Yamamoto N, Matsuura Y, Saitoh T, Akira S. |
Title | DNA-Damage-Induced Nuclear Export of Precursor MicroRNAs Is Regulated by the ATM-AKT Pathway. |
Journal | Cell. 2013. |
Authors | Wan G,Zhang X, Langley R, Liu Y, Hu X, Han C, Peng G, Ellis L, Jones S, Lu X |
Title | Btf and TRAP150 have distinct roles in regulating subcellular mRNA distribution. |
Journal | Nucleus. 2013. |
Authors | Varia S, Potabathula D, Deng Z, Bubulya A, Bubulya PA. |
Title | Nuclear Phosphoinositide-Specific Phospholipase C β1 Controls Cytoplasmic CCL2 mRNA Levels in HIV-1 gp120-Stimulated Primary Human Macrophages. |
Journal | PLoS One. 2013. |
Authors | Spadaro F, Cecchetti S, Purificato C, Sabbatucci M, Podo F, Ramoni C, Gessani S, Fantuzzi L. |
Title | Circular RNAs are abundant, conserved, and associated with ALU repeats. |
Journal | RNA: A Publication of the RNA Society. 2013. |
Authors | Jeck WR, Sorrentino JA, Wang K, Slevin MK, Burd CE, Liu J, Marzluff WF, Sharpless NE. |
Title | Long non-coding antisense RNA controls Uchl1 translation through an embedded SINEB2 repeat. |
Journal | Nature. 2012. |
Authors | Carrieri C, Cimatti L, Biagioli M, Beugnet A, Zucchelli S, Fedele S, Pesce E, Ferrer I, Collavin L, Santoro C, Forrest AR, Carninci P, Biffo S, Stupka E, Gustincich S. |
Title | Characterization of Novel Paternal ncRNAs at the Plagl1 Locus, Including Hymai, Predicted to Interact with Regulators of Active Chromatin. |
Journal | PLoS One. 2012. |
Authors | Iglesias-Platas I, Martin-Trujillo A, Cirillo D, Court F, Guillaumet-Adkins A, Camprubi C, Bourc'his D, Hata K, Feil R, Tartaglia G, Arnaud P, Monk D. |
Title | MxA inhibits hepatitis B virus replication by interaction with core protein HBcAg. |
Journal | Hepatology. 2012. |
Authors | Li N, Zhang L, Chen L, Feng W, Xu Y, Chen F, Liu X, Chen Z, Liu W. |
Title | Reduced DICER1 elicits an interferon response in endometrial cancer cells. |
Journal | Molecular Cancer Research. 2012. |
Authors | Chiappinelli KB, Haynes BC, Brent MR, Goodfellow PJ. |
Title | Monoallelic Expression Determines Oncogenic Progression and Outcome in Benign and Malignant Brain Tumors. |
Journal | Cancer Research. 2011. |
Authors | Walker EJ, Zhang C, Castelo-Branco P, Hawkins C, Wilson W, Zhukova N, Alon N, Novokmet A, Baskin B, Ray P, Knobbe C, Dirks P, Taylor MD, Croul S, Malkin D, Tabori U. |
Title | Identification of new viral genes and transcript isoforms during Epstein-Barr virus reactivation using RNA-seq. |
Journal | Journal of Virology. 2011. |
Authors | Concha M, Wang X, Cao S, Baddoo M, Fewell C, Lin Z, Hulme W, Hedges D, McBride J, Flemington EK. |
Title | Small Noncoding RNA Modulates Japanese Encephalitis Virus Replication and Translation in trans. |
Journal | Virology Journal. 2011. |
Authors | Fan YH, Nadar M, Chen CC, Weng CC, Lin YT, Chang RY. |
Title | Strand antagonism in RNAi: an explanation of differences in potency between intracellularly expressed siRNA and shRNA. |
Journal | Nucleic Acids Resarch. 2011. |
Authors | Jin X, Sun T, Zhao C, Zheng Y, Zhang Y, Cai W, He Q, Taira K, Zhang L, Zhou D. |
Title | Nuclear and cytoplasmic localization of neural stem cell microRNAs. |
Journal | RNA 2011. |
Authors | Jeffries CD, Fried HM, Perkins DO. |
Title | Gene processing control loops suggested by sequencing, splicing, and RNA folding. |
Journal | BMC Bioformatics 2010. |
Authors | Jeffries CD, Perkins DO, Guan X. |
Title | A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells |
Journal | Cancer Cell 2010. |
Authors | >Melo SA, Moutinho C, Ropero S, Calin GA, Rossi S, Spizzo R, Fernandez AF, Davalos V, Villanueva A, Montoya G, Yamamoto H, Schwartz S Jr, Esteller M. |
Title | Molecular Interplay of the Noncoding RNA ANRIL and Methylated Histone H3 Lysine 27 by Polycomb CBX7 in Transcriptional Silencing of INK4a. |
Journal | Mol Cell. 2010. |
Authors | Yap KL, Li S, Muñoz-Cabello AM, Raguz S, Zeng L, Mujtaba S, Gil J, Walsh MJ, Zhou MM. |
Title | The obesity-associated SNPs in intron 1 of the FTO gene affect primary transcript levels. |
Journal | Eur J Hum Genet. 2010. |
Authors | Berulava T, Horsthemke B. |
Title | The Nuclear Transcription Factor RARa Associates with Neuronal RNA Granules and Suppresses Translation. |
Journal | Journal of Biological Chemistry. 283: 20841 - 20847 |
Authors | Chen N, Onisko B, Napoli J. |
Title | Mutation in Nuclear Pore Component NUP155 Leads to Atrial Fibrillation and Early Sudden Cardiac Death |
Journal | Cell. 135: 1017-1027 |
Authors | Zhang X, Chen S, Yoo S, Chakrabarti S, Zhang T, Ke T, Oberti C, Yong SL, Fang F, Li L, de la Fuente R, Wang L, Chen Q, |
Title | Down-regulation of tissue inhibitor of metalloproteinase-3 (TIMP-3) expression is necessary for adipocyte differentiation. |
Journal | Journal of Biological Chemistry. 2010. |
Authors | Bernot D, Barruet E, Poggi M, Bonardo B, Alessi MC, Peiretti F. |
Items | Cat. # | Size | |
---|---|---|---|
Cytoplasmic & Nuclear RNA Purification Kit | 21000 | 50 preps | |
Cytoplasmic & Nuclear RNA Purification Kit | 37400 | 100 preps |
Cytoplasmic and Nuclear RNA Purification Kit
This kit provides a rapid method for the isolation and purification of both cytoplasmic and nuclear RNA from cultured animal cells and small tissue samples. The kit can be used to isolate all sizes of RNA from the cytoplasmic and nuclear RNA fractions, including all small RNA species without any requirement for phenol. Included in the kit are sufficient reagents to perform either 50 cytoplasmic RNA preparations or 25 cytoplasmic and 25 nuclear RNA preparations. Ten samples can be processed in approximately 45 minutes. This kit is also available in a 100 prep size.
Background
In certain circumstances it is desirable to be able to isolate fractionated RNA as opposed to total RNA. For example, it may be preferable to isolate only mature, cytoplasmic RNA for some studies on expression profiling. Alternatively it may be desirable to isolate nuclear RNA in order to investigate and study pre-processed (non-spliced) RNA. Furthermore, this kit can be used to isolate RNA for downstream applications where it is necessary to avoid DNA contamination, since the cytoplasmic fraction has been shown to be free of all traces of genomic DNA.
Kit Specifications
|
|
Maximum Column Binding Capacity
|
Up to 50 µg RNA
|
Maximum Column Loading Volume
|
650 µL
|
Size of RNA Purified
|
All sizes, including small RNA (< 200 nt)
|
Time to Complete 10 Purifications |
45 minutes
|
RNA Yield
HeLa (1 x 106) - Cytoplasmic RNA HeLa (1 x 106) - Nuclear RNA |
15 µg
≤ 3.5 µg |
Storage Conditions and Product Stability
All solutions should be kept tightly sealed and stored at room temperature. These reagents should remain stable for at least 1 year in their unopened containers.
Title | C-MYC-induced upregulation of lncRNA SNHG12 regulates cell proliferation, apoptosis and migration in triple-negative breast cancer |
Journal | Am J Transl Res. 2017 |
Authors | Ouchen Wang, Fan Yang, Yehuan Liu, Lin Lv, Ruimin Ma, Chuanzhi Chen, Jiao Wang, Qiufan Tan,Yue Cheng, Erjie Xia, Yizuo Chen, Xiaohua Zhang |
Title | Long noncoding RNA MHENCR promotes melanoma progression via regulating miR-425/489-mediated PI3K-Akt pathway |
Journal | American Journal of Translational Research. 2017. |
Authors | Chen X, Dong H, Liu S, Yu L, Yan D, Yao X, Sun W, Han D, Gao G. |
Title | Neuronal hemoglobin affects dopaminergic cells’ response to stress |
Journal | Cell Death and Disease. 2017. |
Authors | Codrich M, Bertuzzi M, Russo R, Francescatto M, Espinoza S, Zentilin L, Giacca M, Cesselli D, Beltrami AP, Ascenzi P, Zucchelli S,, Persichetti F, Leanza G, Gustincich S |
Title | Satellite RNAs promote pancreatic oncogenic processes via the dysfunction of YBX1 |
Journal | Nature Communications. 2016. |
Authors | Kishikawa T, Otsuka M,, Yoshikawa T, Ohno M, Ijichi H, Koike K. |
Title | Extracellular Vesicles Including Exosomes Regulate Innate Immune Responses to Hepatitis B Virus Infection |
Journal | Frontiers in Immunology. 2016. |
Authors | Kouwaki T, Fukushima Y, Daito T, Sanada T, Yamamoto N, Mifsud EJ, Leong CR, Tsukiyama-Kohara K, Kohara M, Matsumoto M, Seya T, Oshiumi H |
Title | Evidence for a role of a lncRNA encoded from the p53 tumor suppressor gene in maintaining the undifferentiated state of human myeloid leukemias |
Journal | Gene Reports. 2016. |
Authors | Reisman, D., Gibson, A., Patel, M., & Wang, Y |
Title | The microRNA cluster miR-183/96/182 contributes to long-term memory in a protein phosphatase 1-dependent manner |
Journal | Nature Communications. 2016. |
Authors | Woldemichael BT, Jawaid A, Kremer EA, Gaur N, Krol J, Marchais A, Mansuy IM |
Title | Long noncoding RNA GPC3-AS1 promotes hepatocellular carcinoma progression via epigenetically activating GPC3 |
Journal | The FEBS Journal. 2016. |
Authors | Zhu XT, Yuan JH, Zhu TT, Li YY, Cheng XY |
Title | Global transcript structure resolution of high gene density genomes through multi-platform data integration |
Journal | Nucleic Acids Research. 2016. |
Authors | O'Grady T, Wang X, Höner Zu Bentrup K, Baddoo M, Concha M, Flemington EK |
Title | Long noncoding RNA GIHCG promotes hepatocellular carcinoma progression through epigenetically regulating miR-200b/a/429 |
Journal | Journal of Molecular Medicine. 2016. |
Authors | Sui CJ, Zhou YM, Shen WF, Dai BH, Lu JJ, Zhang MF, Yang JM |
Title | miR-34 activity is modulated through 5′-end phosphorylation in response to DNA damage |
Journal | Nature Communications. 2016. |
Authors | Salzman DW, Nakamura K, Nallur S, Dookwah MT, Metheetrairut C, Slack FJ, Weidhaas JB |
Title | Long noncoding RNA FGFR3-AS1 promotes osteosarcoma growth through regulating its natural antisense transcript FGFR3 |
Journal | Molecular Biology Reports. 2016. |
Authors | Sun, J., Wang, X., Fu, C., Wang, X., Zou, J., Hua, H., & Bi, Z. |
Title | Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism |
Journal | Nature. 2015. |
Authors | Derek A. Oldridge, Andrew C. Wood, Nina Weichert-Leahey, Ian Crimmins, Robyn Sussman, Cynthia Winter, Lee D. McDaniel, Maura Diamond, Lori S. Hart, Shizhen Zhu, Adam D. Durbin, Brian J. Abraham, Lars Anders, Lifeng Tian, Shile Zhang, Jun S. Wei, Javed Khan, Kelli Bramlett, Nazneen Rahman, Mario Capasso, Achille Iolascon, Daniela S. Gerhard, Jaime M. Guidry Auvil, Richard A. Young, Hakon Hakonarson et al. |
Title | Long Non-coding RNA Growth Arrest-specific Transcript 5 (GAS5) Inhibits Liver Fibrogenesis through a Mechanism of Competing Endogenous RNA |
Journal | The Journal of Biological Chemistry. 2015. |
Authors | Fujun Yu, Jianjian Zheng, Yuqing Mao, Peihong Dong, Zhongqiu Lu, Guojun Li, Chuanyong Guo, Zhanju Liu and Xiaoming Fan |
Title | The Role of Long Intergenic Noncoding RNA p21 in Vascular Endothelial Cells |
Journal | DNA and Cell Biology. 2015. |
Authors | He C, Ding JW, Li S, Wu H, Jiang YR, Yang W, Teng L, Yang J, Yang J |
Title | Regulation of p53 during senescence in normal human keratinocytes |
Journal | Aging Cell. 2015. |
Authors | Kim RH, Kang MK, Kim T, Yang P, Bae S, Williams DW, Phung S, Shin KH, Hong C, Park NH |
Title | New non-coding lytic transcripts derived from the Epstein Barr virus latency origin of replication oriP are hyper-edited, bind the paraspeckle protein, NONO/p54nrb, and support lytic viral transcription. |
Journal | Journal of Virology. 2015. |
Authors | Cao S, Moss W, O'Grady T, Concha M, Strong MJ, Wang X, Yu Y, Baddoo M, Zhang K, Fewell C, Lin Z, Dong Y, Flemington EK |
Title | A lncRNA regulates alternative splicing via establishment of a splicing-specific chromatin signature |
Journal | Nature Structural & Molecular Biology. 2015. |
Authors | Inma Gonzalez, Roberto Munita, Eneritz Agirre, Travis A Dittmer, Katia Gysling, Tom Misteli & Reini F Luco |
Title | Microtubule disruption synergizes with oncolytic virotherapy by inhibiting interferon translation and potentiating bystander killing. |
Journal | Nature Communications. 2015. |
Authors | Rozanne Arulanandam, Cory Batenchuk, Oliver Varette, Chadi Zakaria, Vanessa Garcia, Nicole E. Forbes, Colin Davis, Ramya Krishnan, Raunak Karmacharya, Julie Cox, Anisha Sinha, Andrew Babawy, KatherineWaite, EricaWeinstein, Theresa Falls, Andrew Chen, Jeff Hamill, Naomi De Silva, David P. Conrad, Harold Atkins, Kenneth Garson, Carolina Ilkow, Mads Kærn, Barbara Vanderhyden, Nahum Sonenberg, Tommy Alain, Fabrice Le Boeuf, John C. Bell1, & Jean-Simon Diallo |
Title | SP1-induced upregulation of the long noncoding RNA TINCR regulates cell proliferation and apoptosis by affecting KLF2 mRNA stability in gastric cancer. |
Journal | Oncogene. 2015. |
Authors | Xu TP, Liu XX, Xia R, Yin L, Kong R, Chen WM, Huang MD, Shu YQ. |
Title | Developmental regulation of human cortex transcription and its clinical relevance at single base resolution. |
Journal | Nature Neuroscience. 2014. |
Authors | Andrew E Jaffe, Jooheon Shin, Leonardo Collado-Torres, Jeffrey T Leek, Ran Tao, Chao Li, Yuan Gao, Yankai Jia, Brady J Maher, Thomas M Hyde, Joel E Kleinman & Daniel R Weinberger. |
Title | High-Throughput RNA sequencing based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia project. |
Journal | Journal of Virology. 2014. |
Authors | Cao S, Strong MJ, Wang X, Moss WN, Concha M, Lin Z, O'Grady T, Baddoo M, Fewell C, Renne R, Flemington EK. |
Title | Long Noncoding RNA-EBIC Promotes Tumor Cell Invasion by Binding to EZH2 and Repressing E-Cadherin in Cervical Cancer. |
Journal | PLoS ONE. 2014. |
Authors | Ning-xia Sun, Chen Ye, Qian Zhao, Qing Zhang, Chen Xu, Shao-bing Wang, Zhi-jun Jin, Shu-han Sun, Fang Wang, Wen Li mail |
Title | Dramatic Increase in Expression of a Transgene by Insertion of Promoters Downstream of the Cargo Gene. |
Journal | Molecular Biotechnology. 2014. |
Authors | Sakaguchi M, Watanabe M, Kinoshita R, Kaku H, Ueki H, Futami J, Murata H, Inoue Y, Li SA, Huang P, Putranto EW, Ruma IM, Nasu Y, Kumon H, Huh NH. |
Title | Strain-level genomic variation in natural populations of Lebetimonas from an erupting deep-sea volcano. |
Journal | Journal of Virology. 2013. |
Authors | O'Grady T, Cao S, Strong MJ, Concha M, Wang X, Bondurant SS, Adams M, Baddoo M, Srivastav SK, Lin Z, Fewell C, Yin Q, Flemington EK. |
Title | Efficient cellular fractionation improves RNA sequencing analysis of mature and nascent transcripts from human tissues. |
Journal | BMC Biotechnology. 2013. |
Authors | Zaghlool A, Ameur A, Nyberg L, Halvardson J, Grabherr M, Cavelier L, Feuk L. |
Title | Dengue virus subgenomic RNA induces apoptosis through the Bcl-2-mediated PI3k/Akt signaling pathway. |
Journal | Virology. 2013. |
Authors | Liua Y, Liua H, Zoua J, Zhanga B and Yuana Z |
Title | Identification of a long non-coding RNA-associated RNP complex regulating metastasis at the translational step |
Journal | The EMBO Journal. 2013. |
Authors | Gumireddy K, Li A, Yan J, Setoyama T, Johannes GJ, Orom UA, Tchou J, Liu Q, Zhang L, Speicher DW, Calin GA, Huang Q. |
Title | MiR-138 downregulates miRNA processing in HeLa cells by targeting RMND5A and decreasing Exportin-5 stability. |
Journal | Nucleic Acids Research. 2013. |
Authors | Li J, Chen Y, Qin X, Wen J, Ding H, Xia W, Li S, Su X, Wang W, Li H, Zhao Q, Fang T, Qu L, Shao N. |
Title | Zinc-finger antiviral protein mediates retinoic acid inducible gene I-like receptor-independent antiviral response to murine leukemia virus. |
Journal | Proceedings of the National Academy of Sciences of the United States of America. 2013. |
Authors | Lee H, Komano J, Saitoh Y, Yamaoka S, Kozaki T, Misawa T, Takahama M, Satoh T, Takeuchi O, Yamamoto N, Matsuura Y, Saitoh T, Akira S. |
Title | DNA-Damage-Induced Nuclear Export of Precursor MicroRNAs Is Regulated by the ATM-AKT Pathway. |
Journal | Cell. 2013. |
Authors | Wan G,Zhang X, Langley R, Liu Y, Hu X, Han C, Peng G, Ellis L, Jones S, Lu X |
Title | Btf and TRAP150 have distinct roles in regulating subcellular mRNA distribution. |
Journal | Nucleus. 2013. |
Authors | Varia S, Potabathula D, Deng Z, Bubulya A, Bubulya PA. |
Title | Nuclear Phosphoinositide-Specific Phospholipase C β1 Controls Cytoplasmic CCL2 mRNA Levels in HIV-1 gp120-Stimulated Primary Human Macrophages. |
Journal | PLoS One. 2013. |
Authors | Spadaro F, Cecchetti S, Purificato C, Sabbatucci M, Podo F, Ramoni C, Gessani S, Fantuzzi L. |
Title | Circular RNAs are abundant, conserved, and associated with ALU repeats. |
Journal | RNA: A Publication of the RNA Society. 2013. |
Authors | Jeck WR, Sorrentino JA, Wang K, Slevin MK, Burd CE, Liu J, Marzluff WF, Sharpless NE. |
Title | Long non-coding antisense RNA controls Uchl1 translation through an embedded SINEB2 repeat. |
Journal | Nature. 2012. |
Authors | Carrieri C, Cimatti L, Biagioli M, Beugnet A, Zucchelli S, Fedele S, Pesce E, Ferrer I, Collavin L, Santoro C, Forrest AR, Carninci P, Biffo S, Stupka E, Gustincich S. |
Title | Characterization of Novel Paternal ncRNAs at the Plagl1 Locus, Including Hymai, Predicted to Interact with Regulators of Active Chromatin. |
Journal | PLoS One. 2012. |
Authors | Iglesias-Platas I, Martin-Trujillo A, Cirillo D, Court F, Guillaumet-Adkins A, Camprubi C, Bourc'his D, Hata K, Feil R, Tartaglia G, Arnaud P, Monk D. |
Title | MxA inhibits hepatitis B virus replication by interaction with core protein HBcAg. |
Journal | Hepatology. 2012. |
Authors | Li N, Zhang L, Chen L, Feng W, Xu Y, Chen F, Liu X, Chen Z, Liu W. |
Title | Reduced DICER1 elicits an interferon response in endometrial cancer cells. |
Journal | Molecular Cancer Research. 2012. |
Authors | Chiappinelli KB, Haynes BC, Brent MR, Goodfellow PJ. |
Title | Monoallelic Expression Determines Oncogenic Progression and Outcome in Benign and Malignant Brain Tumors. |
Journal | Cancer Research. 2011. |
Authors | Walker EJ, Zhang C, Castelo-Branco P, Hawkins C, Wilson W, Zhukova N, Alon N, Novokmet A, Baskin B, Ray P, Knobbe C, Dirks P, Taylor MD, Croul S, Malkin D, Tabori U. |
Title | Identification of new viral genes and transcript isoforms during Epstein-Barr virus reactivation using RNA-seq. |
Journal | Journal of Virology. 2011. |
Authors | Concha M, Wang X, Cao S, Baddoo M, Fewell C, Lin Z, Hulme W, Hedges D, McBride J, Flemington EK. |
Title | Small Noncoding RNA Modulates Japanese Encephalitis Virus Replication and Translation in trans. |
Journal | Virology Journal. 2011. |
Authors | Fan YH, Nadar M, Chen CC, Weng CC, Lin YT, Chang RY. |
Title | Strand antagonism in RNAi: an explanation of differences in potency between intracellularly expressed siRNA and shRNA. |
Journal | Nucleic Acids Resarch. 2011. |
Authors | Jin X, Sun T, Zhao C, Zheng Y, Zhang Y, Cai W, He Q, Taira K, Zhang L, Zhou D. |
Title | Nuclear and cytoplasmic localization of neural stem cell microRNAs. |
Journal | RNA 2011. |
Authors | Jeffries CD, Fried HM, Perkins DO. |
Title | Gene processing control loops suggested by sequencing, splicing, and RNA folding. |
Journal | BMC Bioformatics 2010. |
Authors | Jeffries CD, Perkins DO, Guan X. |
Title | A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells |
Journal | Cancer Cell 2010. |
Authors | >Melo SA, Moutinho C, Ropero S, Calin GA, Rossi S, Spizzo R, Fernandez AF, Davalos V, Villanueva A, Montoya G, Yamamoto H, Schwartz S Jr, Esteller M. |
Title | Molecular Interplay of the Noncoding RNA ANRIL and Methylated Histone H3 Lysine 27 by Polycomb CBX7 in Transcriptional Silencing of INK4a. |
Journal | Mol Cell. 2010. |
Authors | Yap KL, Li S, Muñoz-Cabello AM, Raguz S, Zeng L, Mujtaba S, Gil J, Walsh MJ, Zhou MM. |
Title | The obesity-associated SNPs in intron 1 of the FTO gene affect primary transcript levels. |
Journal | Eur J Hum Genet. 2010. |
Authors | Berulava T, Horsthemke B. |
Title | The Nuclear Transcription Factor RARa Associates with Neuronal RNA Granules and Suppresses Translation. |
Journal | Journal of Biological Chemistry. 283: 20841 - 20847 |
Authors | Chen N, Onisko B, Napoli J. |
Title | Mutation in Nuclear Pore Component NUP155 Leads to Atrial Fibrillation and Early Sudden Cardiac Death |
Journal | Cell. 135: 1017-1027 |
Authors | Zhang X, Chen S, Yoo S, Chakrabarti S, Zhang T, Ke T, Oberti C, Yong SL, Fang F, Li L, de la Fuente R, Wang L, Chen Q, |
Title | Down-regulation of tissue inhibitor of metalloproteinase-3 (TIMP-3) expression is necessary for adipocyte differentiation. |
Journal | Journal of Biological Chemistry. 2010. |
Authors | Bernot D, Barruet E, Poggi M, Bonardo B, Alessi MC, Peiretti F. |
Copyright © 2021 Norgen Biotek Corp.