Saliva DNA Collection and Preservation Devices Dx
Intended for in vitro diagnostics use.
Note: This product is not available for sale in the United States
Research version available here
Saliva DNA Collection and Preservation Devices Dx
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Overview
- CE-IVDR marked in accordance with the European Commission Regulation (EU) No. 2017/746.
- Ideal for use in in vitro diagnostic workflows
- Reliable and cost-effective
- Non-invasive, user-friendly sample collection
- Sample collection and preservation in one convenient kit
- Samples are non-infectious and can be handled and shipped safely
- Preserved DNA is stable for 2 years at ambient temperature
- High quality DNA is suitable for sensitive downstream applications including PCR, qPCR, sequencing, SNP analysis, microarrays, RFLP and Southern Blot Analysis
- Shipping accessories can be purchased separately
Norgen's Saliva DNA Collection and Preservation Devices are designed for 1) simple and non-invasive saliva collection and 2) preservation of DNA in saliva samples at ambient temperature. Each of the 50 Saliva DNA Collection and Preservation Devices consists of 3 components: (1) Saliva Collection Funnel and Collection Tube, (2) Collection Tube Cap, and (3) Norgen's Saliva DNA Preservative contained within a sealed squeezable ampoule. Saliva samples are collected by spitting inside the Collection Funnel which has been assembled with the Collection Tube. After collecting the required volume of saliva the Collection Funnel is removed and the contents of the Preservative Ampoule are then added and mixed with the collected saliva. The Saliva Collection Tube is subsequently sent to the laboratory for DNA isolation and analysis. DNA can be isolated from the preserved saliva samples using Norgen's Saliva DNA Isolation Kit (Cat# Dx45400). Each of Norgen's Collection Tubes is labeled with a unique serial number that can be used for secure and anonymous tracking of the sample. The saliva DNA in preserved samples is stable for more than 2 years at room temperature. This kit is ideal for collecting and preserving DNA samples for in vitro diagnostic use for medical purposes.
Saliva DNA Preservative
Norgen's Saliva DNA Preservative is an aqueous storage buffer designed for rapid cellular lysis and subsequent preservation of DNA from fresh specimens. The buffer prevents the growth of Gram-negative and Gram-positive bacteria and fungi, and also inactivates viruses allowing the resulting non-infectious samples to be handled and shipped safely. In addition, the buffer eliminates the need to immediately process or freeze samples and allows the samples to be shipped to centralized testing facilities at ambient temperature. The components of the buffer allow samples to be stored for more than 2 years without any detectable DNA degradation.
DNA Isolation from Preservative
Prior to saliva DNA isolation, vortex the Collection Tube containing preserved saliva for 10 seconds and incubate at 55°C for one hour. Saliva DNA can now be isolated from the preserved saliva samples using Norgen’s spin-column based Saliva DNA Isolation Kit Dx (Cat# Dx45400) or other commercially available methods that have been validated for use with Norgen’s Saliva DNA Collection and Preservation Devices.
NOTE: This product is not available for sale in the United States.
Details
Supporting Data
Kit Specifications
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Volume of Saliva Collected
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2 mL
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Volume of Saliva-Preservative Mix
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4 mL
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Preservation Temperature
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Room Temperature
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Preservation time |
Over 2 years at room temperature
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Shelf Life and Handling
- The Collection Device should be kept tightly sealed and stored at room temperature for up to 3 years without any reduction in kit performance (The collection due date is written on the device label).
- Once collected, saliva is stable for more than 2 years when kept tightly sealed and stored at room temperature.
- The Collection Tube, the Collection Funnel and the Device Container of each Individual Saliva DNA Collection and Preservation Device are recyclable.
Kit Components | Cat. 49000 (50 Devices) |
---|---|
Individual Saliva DNA Collection and Preservation Devices | 50 |
Donor Procedure Flowchart | 1 |
Product Insert | 1 |
Individual Saliva DNA Collection and Preservation Device Contents | |
Saliva Collection Funnel and Collection Tube | 1 |
Collection Tube Cap | 1 |
Preservative Ampoule | 1 |
Donor Instructions | 1 |
Documentation
Long Term Stability of DNA Stored in Norgen’s Saliva DNA Preservative
The Range of DNA Yield with Norgen’s Saliva DNA Collection, Preservation and Isolation Kit
Sequencing Analysis of Saliva DNA Isolated using Norgen’s Saliva DNA Collection, Preservation and Isolation Kit
Isolation of High Quality Saliva DNA from Variable Donor Saliva Samples
Inhibitory Effect of Norgen’s Saliva DNA Preservative on the Growth of Bacteria and Yeast
A Comparative Study Between Two Saliva DNA Preservation Systems, and Two Column-Based Saliva DNA Purification Methods
Efficient Restriction Enzyme Digestion of Saliva DNA isolated using Norgen's Saliva DNA Collection, Preservation and Isolation Kits
Comparison of Norgen’s Saliva DNA Collection, Preservation and Isolation Kit to a Leading Competitor’s Kit
DNA Isolation from Saliva Preserved using Norgen’s Saliva DNA Collection and Preservation Device using Beckman Coulter Agencourt
DNA Isolation from Saliva Preserved with Norgen’s Saliva DNA Collection and Preservation Device using Qiagen’s QIAamp DNA Blood
Stability of DNA Stored in Norgen’s Saliva DNA Preservative for 52 Months at Room Temperature
Sex Determination from Saliva DNA Isolated using Norgen's Saliva DNA Collection, Preservation, and Isolation Kit
The Range of DNA Yield and Purity with Norgen's Saliva DNA Collection, Preservation, and Isolation Kit
Column-Based Isolation of DNA from Preserved Saliva Samples Offers High Quality, Consistent, and Rapid DNA Isolation
Citations
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Journal | Food Quality and Preference. 2017 |
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Journal | Molecular Genetics & Genomic Medicine. 2015. |
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Journal | PLOS Genetics. 2014. |
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Journal | Journal of Affective Disorders. 2014. |
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