Norgen’s Saliva Exosome Collection and Preservation Kit is an all-in-one solution designed for 1) simple and non-invasive saliva collection; 2) preservation of exosomes in saliva samples at ambient temperature; and 3) isolation of high quality intact exosomes and exosomal RNA within a laboratory setting.  The Saliva Exosome Collection, Preservation and Isolation Kit contains 50 Individual Saliva Exosome Collection and Preservation Devices, as well as the required reagents for the subsequent laboratory purification of intact exosomes and the isolation of the exosomal RNA from the preserved samples.  Each of the 50 individual Saliva Exosome Collection and Preservation Devices consists of 3 components: (1) Saliva Collection Funnel and Collection Tube that contains Norgen’s Urine Preservative in a dried format, (2) Collection Tube Cap, and (3) ID Label.  Saliva samples are collected by spitting inside the Collection Funnel which has been assembled with the Collection Tube. After collecting the required volume of saliva the Collection Funnel is removed, the Collection Tube is securely capped with Collection Tube Cap. The collected saliva is mixed by gentle inversion for several times till the saliva colour changes into yellow. The Saliva Collection Tube is subsequently sent to the laboratory for the purification of intact exosomes and for the subsequent isolation and analysis of saliva exosomal RNA. The saliva exosomes in preserved samples is stable for 2 years at room temperature.