Intact Exosome Purification

  • Purification and enrichment of intact plasma/serum, urine, cell culture media and saliva exosomes
  • Purified exosomes for use in functional studies prepared in 30 minutes
  • Purify intact exosomes with a size ranging from 40-200 nm depending on sample input type
  • No time-consuming ultracentrifugation, filtration or special syringes required
  • No precipitation reagents, overnight incubation, protease or coagulant treatments required
  • Purified exosomes are free from any protein-bound cell-free circulating RNA
  • Purified exosomes are compatible with NanoSight® or Electron Microscopy for assessing the approximate exosome size range and concentration
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Intact Exosome Purification and Exosomal RNA Isolation

  • Purification and enrichment of intact exosomes from plasma/serum, urine and cell culture media followed by subsequent exosomal RNA isolation from the purified intact exosomes
  • Purified exosomes for use in functional studies prepared in 30 minutes
  • Purify intact exosomes with a size ranging from 40-200 nm depending on sample input type
  • Isolate all sizes of exosomal and extracellular vesicle RNA, including microRNA, irrespective of size or GC content, without bias
  • Purify high-quality RNA in 15-20 minutes
  • Concentrate isolated RNA into a flexible elution volume ranging from 50 µL to 100 µL
  • The purified exosomes are compatible with NanoSight® or Electron Microscopy for assessing the approximate exosome size range and concentration
  • The purified RNA is suitable for a variety of downstream applications, including Small RNA Sequencing. Find out more information on Norgen's NGS services
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Intact Exosome Purification, Exosomal RNA and Free-Circulating RNA Isolation

  • Purification and enrichment of intact exosomes from plasma/serum and urine followed by subsequent RNA isolation from both the purified intact exosomes and the circulating cell-free RNA
  • Purified exosomes for use in functional studies prepared in 30 minutes
  • Purify high-quality exosomal and cell-free circulating RNA (cfc-RNA) in 15-20 minutes
  • Purify intact exosomes with a size ranging from 40-200 nm depending on sample input type
  • The purified exosomes are free from any protein-bound cell-free circulating RNA
  • Sequential isolation of all sizes of exosomal/extracellular vesicle RNA and cfc-RNA, including microRNA in two separate fractions irrespective of size or GC content, without bias
  • Concentrate isolated RNA into a flexible elution volume ranging from 50 µL to 100 µL
  • The purified exosomes are compatible with NanoSight® or Electron Microscopy for assessing the approximate exosome size range and concentration
  • The purified RNA is suitable for a variety of downstream applications, including Small RNA Sequencing. Find out more information on Norgen's NGS services
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RNA Isolation from Purified Intact Exosomes

  • Isolate all sizes of exosomal and extracellular vesicle RNA, including microRNA, from previously purified exosomes
  • Bind and elute all RNA irrespective of size or GC content, without bias
  • No phenol extractions, Proteinase K treatment or carrier RNA required
  • Concentrate isolated RNA into a flexible elution volume ranging from 50 µL to 100 µL
  • Purify high-quality RNA in 15-20 minutes
  • Compatible with exosome and extracellular vesicles purified using Norgen’s exosome purification technology or using any other exosome purification technology such as ultracentrifugation, Exoquick, filtration or others
  • Purified RNA is suitable for a variety of downstream applications, including Small RNA Sequencing. Find out more information on Norgen's NGS services
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Exosome Depletion

  • Efficient depletion of cow's exosomes from Fetal Bovine Serum or any other serum source prior to use as a growth supplement in culture medium
  • Deplete exosome-sized vesicles from versatile serum volumes of up to 280 mL
  • No protease treatment required
  • No time-consuming ultracentrifugation
  • No precipitation reagents or overnight incubation required
  • Depleted FBS has no detectable cow’s miRNA
  • The depleted FBS provides the same cellular growth rates as the standard FBS
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Meta Description: 
Get fast and accurate results with our exosome and RNA isolation kits. Isolate from plasma/serum, urine, cell culture media and saliva samples.