Plasma/Serum Circulating and Exosomal RNA Purification Kits (Slurry Format) For rapid and simple isolation of circulating RNA including exosomal RNA from plasma/serum samples For research use only and NOT intended for in vitro diagnostics. Powered by Bioz Plasma/Serum Circulating and Exosomal RNA Purification Kits (Slurry Format) For rapid and simple isolation of circulating RNA including exosomal RNA from plasma/serum samples Price USD$585.00 SKU 51000 Format Mini Slurry Slurry High Throughput Slurry Maxi Slurry Size 50 Preps Quantity Overview Details Documentation Citations Overview Isolate all sizes of circulating and exosomal RNA, including microRNA Versatile plasma and serum input volumes Concentrate circulating and exosomal RNA into small elution volumes Isolate inhibitor-free circulating and exosomal RNA Bind and elute all RNA irrespective of size or GC content, without bias Available in Spin Column or 96-well plate formats Process 96-well plates using vacuum or centrifugation Purified RNA is suitable for a variety of downstream applications, including Small RNA Sequencing. Find out more information on Norgen's NGS services Compatible with Streck Cell-Free RNA BCT® Tubes Purification is based on Norgen’s proprietary resin matrix These kits are able to isolate all sizes of circulating and exosomal RNA, including microRNA, without the use of phenol or chloroform. The slurry format provides an advantage over other available kits in that it does not require extension tubes for the purification of free-circulating and exosomal RNA from large sample volumes. RNA can be isolated from either fresh or frozen samples using this kit. This kit is suitable for the isolation of RNA from serum or plasma prepared from blood collected only on either EDTA or citrate. Plasma samples prepared from blood collected on heparin should not be used as heparin can significantly interfere with many downstream applications including RT-PCR. The purified plasma/serum free-circulating and exosomal RNA is eluted in an elution solution that is compatible with PCR, qPCR, methylation-sensitive reverse transcription qPCR, reverse transcription PCR, Northern blotting, RNase protection and primer extension, expression array assays, and NGS. Free-circulating plasma and serum RNA can serve as both tumor- and fetal-specific markers for cancer detection and prenatal diagnosis. As well, free-circulating RNAs have the potential to provide biomarkers for other disease states. Free-circulating RNA in plasma or serum are usually present as short fragments of less than 1000nt, and free-circulating miRNA (21nt) can also be found in plasma and serum. Plasma/Serum Circulating and Exosomal RNA Purification Kit (Slurry) Norgen's Plasma/Serum Circulating and Exosomal RNA Purification Kit (Slurry Format) provides a fast, reliable and simple procedure for isolating circulating RNA and exosomal RNA from plasma and serum samples ranging from 0.25 mL to 5 mL. Plasma/Serum Circulating and Exosomal RNA Purification Mini Kit (Mini Slurry) Norgen's Plasma/Serum Circulating and Exosomal RNA Purification Mini Kit (Slurry Format) provides a fast, reliable and simple procedure for isolating circulating and exosomal RNA from plasma and serum samples ranging from 0.25 mL to 2 mL. Plasma/Serum Circulating and Exosomal RNA Purification 96-Well Kit (High Throughput Slurry) Norgen's Plasma/Serum Circulating and Exosomal RNA Purification 96-Well Kit (Slurry Format) provides a high throughput method for isolating circulating and exosomal RNA from plasma and serum samples using either a vacuum manifold or centrifugation. Plasma/Serum Circulating and Exosomal RNA Purification Maxi Kit (Maxi Slurry) Norgen's Plasma/Serum Circulating and Exosomal RNA Purification Maxi Kit (Slurry Format) provides a fast, reliable and simple procedure for isolating circulating RNA and exosomal RNA from various amounts of plasma/serum ranging from 2 mL to 5 mL. Details Supporting Data Previous Figure 1. Isolation and Detection of Circulating RNA from Different Plasma Volumes. Norgen's Plasma/Serum Circulating RNA Purification Mini Kit (Slurry Format) was used to isolate circulating RNA from 0.5mL, 1mL and 2mL plasma. Three microlitres of the purified RNA was then used as the template in RT-qPCR reactions to detect the human 5S gene. The 5S housekeeping gene was detected from all plasma sample volumes used. The amplification of the 5S rRNA showed an increasing amount of RNA with increasing the sample input volume. This is represented by the decrease of the Ct value with increasing the sample input volume. RNA isolated from 0.5mL plasma is represented by the Red line, RNA isolated from 1mL plasma is represented by the Green line whereas RNA isolated from 2mL plasma is represented by the Blue line. The black line corresponds to the no template control. Figure 2. Effective Isolation of Plasma Circulating RNA from Different Volumes. Norgen's Plasma/Serum Circulating RNA Purification Mini Kit (Slurry Format) was used to isolate circulating RNA from 0.5mL, 1mL and 2mL plasma. Three microlitres of the purified RNA was then used as the template in RT-qPCR reactions to detect the human 5S gene. The 5S housekeeping gene was detected from all plasma sample volumes used. The amplification of the 5S rRNA showed an increasing amount of RNA with increasing the sample input volume. This is represented by the decrease of the Ct value with increasing the sample input volume. Average Ct. values for the amplification of the 5S rRNA isolated from 0.5mL plasma is represented by the Red bar, Average Ct. values for the amplification of the 5S rRNA isolated from 1mL plasma is represented by the Green bar whereas Average Ct. values for the amplification of the 5S rRNA isolated from 2mL plasma is represented by the blue bar. Figure 3. Effective and Consistent Detection of Plasma Exosome RNA. Norgen's Plasma/Serum Circulating and Exosomal RNA Isolation Kits can effectively isolate RNA from plasma. Plasma Exosome RNA was isolated from 500 µL of human plasma prepared from blood collected on citrate, EDTA or Heparin in triplicates using Norgen's Plasma/Serum RNA Isolation Kit (blue), a ExoQuick Exosome Precipitation Reagent (green) and Qiagen’s QIAzol extraction followed by a modified Qiagen's RNeasy Mini Kit cleanup (red). Stem loop RT-qPCR using primers specific to miR-21 and miR-16 as well as the housekeeping 5S rRNA was performed. In brief, three microliters of the 100 µL isolated RNA was then subjected to a 20 µL reverse transcription using 5S rRNA, miR-21 and miR-16 stem-loop reverse primer or reveres primer. Three microliters of the reverse transcription was used in a 20 µL real-time PCR reaction with primers to detect the human miR-21, human miR-16 and the 5S rRNA. Norgen's Plasma/Serum Exosome RNA Isolation Kit is the only product that showed consistent detection of all tested transcripts with the highest quality regardless the type of the anti-coagulant used for blood collection. Figure 4. Isolation and Detection of Circulating RNA from Different Plasma Volumes. Norgen's Plasma/Serum Circulating RNA Purification Maxi Kit (Slurry Format) was used to isolate circulating RNA from 2mL, 3mL and 5mL plasma. Three microlitres of the purified RNA was then used as the template in RT-qPCR reactions to detect the human 5S gene. The 5S housekeeping gene was detected from all plasma sample volumes used. The amplification of the 5S rRNA showed an increasing amount of RNA with increasing the sample input volume. This is represented by the decrease of the Ct value with increasing the sample input volume. RNA isolated from 2mL plasma is represented by the Red line, RNA isolated from 3mL plasma is represented by the Green line whereas RNA isolated from 5mL plasma is represented by the Blue line. The black line corresponds to the no template control. Figure 5. Effective Isolation of Plasma Circulating RNA from Different Volumes. Norgen's Plasma/Serum Circulating RNA Purification Maxi Kit (Slurry Format) was used to isolate circulating RNA from 2mL, 3mL and 5mL plasma. Three microlitres of the purified RNA was then used as the template in RT-qPCR reactions to detect the human 5S gene. The 5S housekeeping gene was detected from all plasma sample volumes used. The amplification of the 5S rRNA showed an increasing amount of RNA with increasing the sample input volume. This is represented by the decrease of the Ct value with increasing the sample input volume. Average Ct. values for the amplification of the 5S rRNA isolated from 2mL plasma is represented by the Red bar, Average Ct. values for the amplification of the 5S rRNA isolated from 3mL plasma is represented by the Green bar whereas Average Ct. values for the amplification of the 5S rRNA isolated from 5mL plasma is represented by the blue bar. Next Click for expanded view Kit Specifications - Spin Column Minimum Plasma/Serum Input 0.25 mL Maximum Plasma/Serum Input 2 mL Size of RNA Purified All sizes, including microRNA Time to Complete Purification < 40 minutes Cat.51000 Storage Conditions and Product Stability It is recommended to warm up Slurry C1 and Lysis Buffer A for 20 minutes at 60°C if any salt precipitation (crystallization) is observed. Slurry C1 contains grey resin that will not disappear by warming up. Component Cat. 51000 (50 preps) Cat. 29500 (96 preps) Cat. 42800 (50 preps) Cat. 50900 (25 preps) Slurry C1 - - - 6 mL Slurry C2 12 mL - 12 mL - Slurry C3 - 20 mL - - Lysis Buffer A 2 x 130 mL 4 x 100 mL 2 x 130 mL 2 x 130 mL Wash Solution A 38 mL 2 x 38 mL 38 mL 18 mL Elution Solution A 6 mL 20 mL 6 mL 6 mL Mini Filter Spin Columns 50 - 50 25 96-Well Filter Plate - 1 - - Adhesive Tape - 1 - - Collection Tubes 50 - 50 25 96-Well Collection Plate - 1 - - Elution Tubes (1.7 mL) 50 - 50 25 96-Well Elution Plate - 1 - - Product Insert 1 1 1 1 Documentation PROTOCOLS (42800) Plasma/Serum Circulating and Exosomal RNA Purification Kit (Slurry) - Protocol (50 prep) (51000) Plasma/Serum Circulating and Exosomal RNA Purification Mini Kit (Mini Slurry) - Protocol (50 prep) (29500) Plasma/Serum Circulating and Exosomal RNA Purification 96-Well Kit (High Throughput Slurry) - Protocol (96-well) (50900) Plasma/Serum Circulating and Exosomal RNA Purification Maxi Kit (Maxi Slurry) - Protocol (25 prep) SUPPLEMENTARY PROTOCOLS Plasma/Serum Circulating and Exosomal RNA Purification Kit (Slurry Format) - Supplementary Protocol APPLICATION NOTES Plasma/Serum Circulating and Exosomal RNA Purification Kit (Slurry Format) Effect of Microrna Gc Content On RNA Purification Efficiency - Application Note Effect of microRNA GC Content on RNA Purification Efficiency SAFETY DATA SHEETS (42800) Plasma/Serum Circulating and Exosomal RNA Purification Kit (Slurry Format) - Safety Data Sheet (51000) Plasma/Serum Circulating and Exosomal RNA Purification Mini Kit (Slurry Format) - Safety Data Sheet (29500) Plasma/Serum Circulating and Exosomal RNA Purification 96-Well Kit (Slurry Format) - Protocol (96-well) - Safety Data Sheet (50900) Plasma/Serum Circulating and Exosomal RNA Purification Maxi Kit (Slurry Format) - Safety Data Sheet POSTERS Variation Between The Purification Efficiency of Microrna With Different Gc Content In Biological and Clinical Specimens RELATED BLOGS 3 Reasons why Norgen’s Industry-Leading Patented RNA Purification Technology is Best-in-Class How to Reduce False Negative SARS-CoV-2 Results with Silicon Carbide Citations Mini, High Throughput (51000, 29500) Title Lateral Flow Test (LFT) Detects Cell-Free MicroRNAs Predictive of Preterm Birth Directly from Human Plasma Journal Advanced NanoBiomed Research. 2022. 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Authors Kyle V Marra, Edith Aguilar, Wei Guoqin, Ayumi Usui-Ouchi, Yochiro Ideguchi, Susumu Sakimoto, Martin Friedlander Title Clinical utility of cerebrospinal fluid-derived circular RNAs in lung adenocarcinoma patients with brain metastases Journal Journal of Translational Medicine. 2022. Authors Zhen Wang, Ruoying Yu, Xiaoxi Chen, Hua Bao, Ran Cao, An-Na Li, Qiuxiang Ou, Hai-Yan Tu, Qing Zhou, Xue Wu, Zhi-Bo Lin & Yi-Long Wu Title Identification of key microRNAs in exosomes derived from patients with the severe acute pancreatitis Journal Asian Journal of Surgery. 2022. Authors Yuanxu Qu, Yixuan Ding, Jiongdi Lu, Yuchen Jia, Chunjing Bian, Yulin Guo, Zhi Zheng, Wentong Mei, Feng Cao, Fei Li Title Hatching is modulated by microRNA-378a-3p derived from extracellular vesicles secreted by blastocysts Journal PNAS. 2022. Authors Krishna Chaitanya Pavani, Tim Meese, Osvaldo Bogado Pascottini, XueFeng Guan, Xiaoyuan Lin, Luc Peelman, Joachim Hamacher, Filip Van Nieuwerburgh, Dieter Deforce, Annekatrien Boel, Bj€orn Heindryckx, Kelly Tilleman, Ann Van Soom, Bart M. Gadella, An Hendrix, and Katrien Smits Title Deep sequencing of circulating exosomal microRNA allows non-invasive glioblastoma diagnosis Journal NPJ Precision Oncology. 2018. Authors Saeideh Ebrahimkhani, Fatemeh Vafaee, Susannah Hallal, Heng Wei, Maggie Yuk T. Lee, Paul E. Young, Laveniya Satgunaseelan, Heidi Beadnall, Michael H. Barnett, Brindha Shivalingam, Catherine M. Suter, Michael E. Buckland, Kimberley L. Kaufman Title Exosomal microRNA signatures in multiple sclerosis reflect disease status Journal Scientific Reports. 2017. Authors Saeideh Ebrahimkhani, Fatemeh Vafaee, Paul E. Young, Suzy S. J. Hur, Simon Hawke, Emma Devenney, Heidi Beadnall, Michael H. Barnett, Catherine M. Suter & Michael E. Buckland Title Different levels of serum microRNAs in prostate cancer and benign prostatic hyperplasia: evaluation of potential diagnostic and prognostic role Journal Onco Targets Therapy. 2016. Authors Cochetti G, Poli G, Guelfi G, Boni A, Egidi MG, Mearini E. Title Schistosomal miRNAs isolated from Extracellular Vesicles in sera of infected patients; a new tool for diagnosis and follow-up of human schistosomiasis Journal The Journal of Infectious Disease. 2016. Authors Tal Meningher, Galya Lerman, Neta Regev-Rudzki, Daniel Gold, Iddo Ben-Dov, Yechezkel Sidi, Dror Avni, and Eli Schwartz Title Plasma DNA and RNA differentially impact coagulation during abdominal sepsis – an explorative study Journal Journal of Surgical Research. 2016. 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Authors Arianna Rocca, Francesco Martelli, Serena Delbue, Pasquale Ferrante, Dario Bartolozzi, Alberta Azzi, Simone Giannecchini Title Expression Profiling Of MiRNAs In Pediatric Bronchopulmonary Dysplasia Journal American Thoracic Society International Conference Abstracts. 2015. Authors Judie A. Howrylak, Melody Pham, Christiana Oji-Mmuo, Susan DiAngelo, Debra Spear, Kimberly Group, Roopa Siddaiah, Neal Thomas , Patricia Silveyra Title Dose-dependent Modulation of Lipid Parameters, Cytokines and RNA by δ-tocotrienol in Hypercholesterolemic Subjects Restricted to AHA Step-1 Diet Journal British Journal of Medicine and Medical Research. 2014. Authors Asaf A. Qureshi, Dilshad A. Khan , Wajiha Mahjabeen and Nilofer Qureshi Title Prognostic serum miRNA biomarkers associated with Alzheimer’s disease shows concordance with neuropsychological and neuroimaging assessment. Journal Molecular Psychiatry. 2014. Authors L Cheng, J D Doecke, R A Sharples, V L Villemagne, C J Fowler, A Rembach, R N Martins, C C Rowe, S L Macaulay, C L Masters, A F Hill. Spin Column (42800) Title Extracellular vesicle-encapsulated microRNAs as novel biomarkers of lung health Journal AJRCCM. 2022. Authors Christina M. Eckhardt, Simone Gambazza, Tessa R. Bloomquist, et al. Title Salivary Exosomal MicroRNA-486-5p and MicroRNA-10b-5p in Oral and Oropharyngeal Squamous Cell Carcinoma Journal Medicina. 2022. Authors Cosmin Ioan Faur, Rareș Călin Roman, Ancuța Jurj, Lajos Raduly, Oana Almășan, Horațiu Rotaru, Magdalena Chirilă, Mădălina Anca Moldovan, Mihaela Hedeșiu and Cristian Dinu Title One-Step and Real-Time Detection of microRNA-21 in Human Samples for Lung Cancer Biosensing Diagnosis Journal Anal. Chem. 2022. Authors Olalla Calvo-Lozano, Pablo García-Aparicio, Lajos-Zsolt Raduly, Maria Carmen Estévez, Ioana Berindan-Neagoe, Manuela Ferracin, and Laura M. Lechuga Title Plasma cell-free RNA profiling distinguishes cancers from pre-malignant conditions in solid and hematologic malignancies Journal npj Precision Oncology. 2022. Authors Breeshey Roskams-Hieter, Hyun Ji Kim, Pavana Anur, Josiah T. Wagner, Rowan Callahan, Elias Spiliotopoulos, Charles Ward Kirschbaum, Fehmi Civitci, Paul T. Spellman, Reid F. Thompson, Khashayar Farsad, Willscott E. Naugler & Thuy T. M. Ngo Title Irreversible alteration of extracellular vesicle and cell-free messenger RNA profiles in human plasma associated with blood processing and storage Journal Scientific Reports. 2022. Authors Hyun Ji Kim, Matthew J. Rames, Samuel Tassi Yunga, Randall Armstrong, Mayu Morita, Anh T. P. Ngo, Owen J. T. McCarty, Fehmi Civitci, Terry K. Morgan & Thuy T. M. Ngo Title Salivary miRNA Expression in Children With Persistent Post-concussive Symptoms Journal Front Public Health. 2022. Authors Katherine E. Miller, James P. MacDonald, Lindsay Sullivan, Lakshmi Prakruthi Rao Venkata, Junxin Shi, Keith Owen Yeates, Su Chen, Enas Alshaikh, H. Gerry Taylor, Amanda Hautmann, Nicole Asa, Daniel M. Cohen, Thomas L. Pommering, Elaine R. Mardis, Jingzhen Yang Title A Pilot Study of miRNA Expression Profile as a Liquid Biopsy for Full-Marathon Participants Journal Sports. 2021. Authors Tomoaki Kuji, Takehito Sugasawa, Shin-ichiro Fujita, Seiko Ono, Yasushi Kawakami and Kazuhiro Takekoshi Title RNA profiles reveal signatures of future health and disease in pregnancy Journal Nature. 2022. Authors Rasmussen M, Reddy M, Nolan R, Camunas-Soler J, Khodursky A, Scheller NM, Cantonwine DE, Engelbrechtsen L, Mi JD, Dutta A, Brundage T, Siddiqui F, Thao M, Gee EPS, La J, Baruch-Gravett C, Santillan MK, Deb S, Ame SM, Ali SM, Adkins M, DePristo MA, Lee M, Namsaraev E, Gybel-Brask DJ, Skibsted L, Litch JA, Santillan DA, Sazawal S, Tribe RM, Roberts JM, Jain M, Høgdall E, Holzman C, Quake SR, Elovitz MA, McElrath TF Title Whole Blood Holding Time Prior to Plasma Processing Alters microRNA Expression Profile Journal Frontiers Genetics . 2022. Authors Kim SH, MacIntyre DA, Sykes L, Arianoglou M, Bennett PR, Terzidou V Title Plasma cell-free RNA profiling distinguishes cancers from pre-malignant conditions in solid and hematologic malignancies Journal NPJ precision oncology . 2022. Authors Roskams-Hieter B, Kim HJ, Anur P, Wagner JT, Callahan R, Spiliotopoulos E, Kirschbaum CW, Civitci F, Spellman PT, Thompson RF, Farsad K, Naugler WE, Ngo TTM Title Irreversible alteration of extracellular vesicle and cell-free messenger RNA profiles in human plasma associated with blood processing and storage. Journal Scientific Reports. 2022. Authors Kim, H., Rames, M.J., Tassi Yunga, S. et al. Title Maternal plasma miRNAs as potential biomarkers for detecting risk of small-for-gestational-age births Journal EBioMedicine. 2020. Authors Kim, S. H., MacIntyre, D. A., Binkhamis, R., Cook, J., Sykes, L., Bennett, P. R., & Terzidou, V. Title Circulating microvesicle number, function and small RNA content vary with age, gender, smoking status, lipid and hormone profiles Journal Thrombosis Research. 2017. Authors Anoop K. Enjeti, Anita Ariyarajah, Angel D'Crus, Michael Seldon, Lisa F. Lincz Title Development and Clinical Utility of a Blood-Based Test Service for the Rapid Identification of Actionable Mutations in Non–Small Cell Lung Carcinoma Journal The Journal of Molecular Diagnostics. 2017. Authors Hestia Mellert, Trudi Foreman, Leisa Jackson, Dianna Maar, Scott Thurston, Kristina Koch, Amanda Weaver, Samantha Cooper, Nicholas Dupuis, Ubaradka G. Sathyanarayana, Jakkie Greer, Westen Hahn, Dawne Shelton, Paula Stonemetz, Gary A. Pestano Title MiR-200a/ZEB1 Pathway in Liver Fibrogenesis of Biliary Atresia Journal International Journal of Medical, Health, Biomedical, Bioengineering and Pharmaceutical Engineering. 2017. Authors Hai-Ying Liu, Yi-Hao Chen, Shu-Yin Pang, Feng-Hua Wang, Xiao-Fang Peng, Li-Yuan Yang, Zheng-Rong Chen, Yi Chen, Bing Zhu Title Different levels of serum microRNAs in prostate cancer and benign prostatic hyperplasia: evaluation of potential diagnostic and prognostic role Journal OncoTargets and Therapy. 2016. Authors Cochetti G, Poli G, Guelfi G, Boni A, Egidi MG, Mearini E. Title Pancreatic acinar cells employ miRNAs as mediators of intercellular communication to participate in the regulation of pancreatitis-associated macrophage activation Journal Mediators of Inflammation. 2016. Authors Yong Zhao, Hao Wang, Ming Lu, Xin Qiao, B. Sun, Weihui Zhang, and Dongbo Xue Title microRNA expression profiling on individual breast cancer patients identifies novel panel of circulating microRNA for early detection Journal Scientific Reports. 2016. Authors Hamam R, Ali AM, Alsaleh KA, Kassem M, Alfayez M, Aldahmash A, Alajez NM Title Expression profiling of selected microRNA signatures in plasma and tissues of Saudi colorectal cancer patients by qPCR Journal Oncology Letters. 2016. Authors Al-Sheikh YA, Ghneim HK, Softa KI, Al-Jobran AA, Al-Obeed O, Mohamed MA, Abdulla M, Aboul-Soud MA Title Meeting report: discussions and preliminary findings on extracellular RNA measurement methods from laboratories in the NIH Extracellular RNA Communication Consortium Journal Journal of Extracellular Vesicles. 2015. Authors Laurent LC,, Abdel-Mageed AB, Adelson PD, Arango J, Balaj L,, Breakefield X,,, Carlson E, Carter BS, Majem B, Chen CC, Cocucci E, Danielson K, Courtright A, Das S, Abd Elmageed ZY, Enderle D, Ezrin A, Ferrer M, Freedman J, Galas D,, Gandhi R, Huentelman MJ, Van Keuren-Jensen K, Kalani Y, Kim Y, Krichevsky AM, Lai C,, Lal-Nag M, Laurent CD, Leonardo T, Li F, Malenica I, Mondal D, Nejad P, Patel T,, Raffai RL,, Rubio R, Skog J, Spetzler R, Sun J, Tanriverdi K, Vickers K,, Wang L, Wang Y, Wei Z, Weiner HL, Wong D, Yan IK, Yeri A, Gould S. Title Data on individual PCR efficiency values as quality control for circulating miRNAs Journal Data in Brief. 2015. Authors Anna Brunet-Vega, Carles Pericay, María Elisa Quílez, María José Ramírez-Lázaro, Xavier Calvet, Sergio Lario Title Plasma MicroRNAs as Novel Biomarkers for Patients with Intraductal Papillary Mucinous Neoplasms of the Pancreas Journal Cancer Prevention Research. 2015. Authors Jennifer Permuth-Wey, Dung-Tsa Chen, William J. Fulp, Sean J. Yoder, Yonghong Zhang, Christina Georgeades, Kazim Husain, Barbara Ann Centeno, Anthony M. Magliocco, Domenico Coppola, and Mokenge Malafa Title Blocking of targeted microRNAs from next-generation sequencing libraries Journal Nucleic Acids Research. 2015. Authors Brian S. Roberts, Andrew A. Hardigan, Marie K. Kirby, Meredith B. Fitz-Gerald, C. Mel Wilcox, Robert P. Kimberly and Richard M. Myers Title Plasma circulating-microRNA profiles are useful for assessing prognosis in patients with cytogenetically normal myelodysplastic syndromes. Journal Modern Pathology. 2014. Authors Zhuang Zuo, Sourindra Maiti, Shimin Hu, Sanam Loghavi, George A Calin, Guillermo Garcia-Manero, Hagop M Kantarjian, L Jeffrey Medeiros, Laurence JN Cooper and Carlos E Bueso-Ramos. Title Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell-free blood. Journal Journal of Extracellular Vesicles. 2014. Authors Cheng L, Sharples RA, Scicluna BJ, Hill AF. Title Three-Mode Electrochemical Sensing of Ultra-Low MicroRNA Levels. Journal Journal of the American Chemical Society. 2013. Authors Labib M, Khan N, Ghobadloo SM, Cheng J, Pezacki JP, Berezovski MV. Maxi (50900) Title Loa loa and Onchocerca ochengi miRNAs detected in host circulation Journal Molecular and Biochemical Parasitology. 2014. Authors Lucienne Tritten, Maeghan O’Neill, Samuel Wanji, Abdel Njouendoui, Fanny Fombad, Jonas Kengne-Ouaffo, Charles Mackenzie, Timothy Geary. Title Detection of Circulating Parasite-Derived MicroRNAs in Filarial Infections Journal PLOS Neglected Tropical Diseases. 2014. Authors Lucienne Tritten, Erica Burkman, Andrew Moorhead, Mohammed Satti, James Geary, Charles Mackenzie, Timothy Geary. Title Loa loa and Onchocerca ochengi miRNAs detected in host circulation Journal Molecular and Biochemical Parasitology. 2014. Authors Lucienne Tritten, Maeghan O’Neill, Samuel Wanji, Abdel Njouendoui, Fanny Fombad, Jonas Kengne-Ouaffo, Charles Mackenzie, Timothy Geary. Title Detection of Circulating Parasite-Derived MicroRNAs in Filarial Infections Journal PLOS Neglected Tropical Diseases. 2014. Authors Lucienne Tritten, Erica Burkman, Andrew Moorhead, Mohammed Satti, James Geary, Charles Mackenzie, Timothy Geary. Related Services NGS RNA Isolation Related Products Plasma/Serum RNA Purification Maxi Kit RNase-Free DNase I Kit Plasma/Serum Exosome Purification and RNA Isolation Mini Kit
Plasma/Serum Circulating and Exosomal RNA Purification Kits (Slurry Format) For rapid and simple isolation of circulating RNA including exosomal RNA from plasma/serum samples For research use only and NOT intended for in vitro diagnostics. Powered by Bioz Plasma/Serum Circulating and Exosomal RNA Purification Kits (Slurry Format) For rapid and simple isolation of circulating RNA including exosomal RNA from plasma/serum samples Price USD$585.00 SKU 51000 Format Mini Slurry Slurry High Throughput Slurry Maxi Slurry Size 50 Preps Quantity